Cas No.: | 104561-41-3 |
Chemical Name: | Benzoic acid,4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl]- |
SMILES: | OC(=O)C1=CC=C(C=C1)C#CC2=CC3=C(C=C2)C(C)(C)CCC3(C)C |
Formula: | C23H24O2 |
M.Wt: | 332.43546 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation[1]. |
In Vitro: | EC23 (AGN 190205) induces neural differentiation accompanying by elevated levels of stathmin and profilin-1. EC23 induces the expression of known cellular retinoid binding proteins in the TERA2.cl.SP12 cell line[1]. |
References: | [1]. Maltman DJ, et al. Proteomic profiling of the stem cell response to retinoic acid and synthetic retinoid analogues: identification of major retinoid-inducible proteins. Mol Biosyst. 2009 May;5(5):458-71. |