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  2. Metabolic Enzyme/Protease Immunology/Inflammation GPCR/G Protein Neuronal Signaling
  3. Endogenous Metabolite Histamine Receptor
  4. Olopatadine

Olopatadine 是一種具有口服活性和選擇性的組胺 1 (H1) 受體拮抗劑，也是肥大細(xì)胞穩(wěn)定劑。Olopatadine 可以防止人結(jié)膜肥大細(xì)胞釋放免疫刺激的促炎介質(zhì)。Olopatadine 可用于過敏性結(jié)膜炎的研究。

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Olopatadine Chemical Structure

Olopatadine Chemical Structure

CAS No. : 113806-05-6

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規(guī)格 價(jià)格 是否有貨 數(shù)量
5 mg ￥1440
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Other Forms of Olopatadine:

查看 Histamine Receptor 亞型特異性產(chǎn)品:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Olopatadine is an orally active and selective histamine 1 (H1) receptor antagonist and a mast cell stabilizer. Olopatadine prevents immunologically stimulated pro-inflammatory mediator release from human conjunctival mast cells. Olopatadine can be used for researching allergic conjunctivitis[1][2].

IC50 & Target[1]

H1 Receptor

 

體外研究
(In Vitro)

Olopatadine inhibits anti-IgE antibody-mediated release of TNF-α from human conjunctival mast cells, and significantly decreases the mast cell supernatant-mediated upregulation of ICAM (intercellular adhesion molecule)-1 on human conjunctival epithelial cells in vitro[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
分子量

337.41

Formula

C21H23NO3
CAS 號(hào)
結(jié)構(gòu)分類
初始來源
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
純度 & 產(chǎn)品資料
參考文獻(xiàn)

  • 摩爾計(jì)算器

  • 稀釋計(jì)算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
Olopatadine
目錄號(hào)：
HY-W062109
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