Soluble in Water (100 mM), DMSO (100 mM),or Ethanol (25 mM)
REVIEW Medetomide''s active isomer which is a potent, highly selective alfa2-adrenoceptor agonist. In vivo; displays hypothermic, hypotensive, bradycardic, anxiolytic, sedative and analgesic effects.
REFERENCES
[1]
Fisher et al (1991) Antinociceptive properties of intrathecal dexmedetomidine in rats. Eur.J.Pharmacol. 192 221.
[2]
Virtanen et al (1988) Characterization of the selectivity, specificity and potency of medetomidine as an a2-adrenoceptor agonist. Eur.J.Pharmacol. 150 9.
[3]
Scheinin et al (1989) Medetomidine - a novel a2-adrenoceptor agonist: a review of its pharmacodynamic effects. Prog.Neuro-Psychopharm.Biol.Psychiat. 13 635.
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