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(1S,3S)-3,5,12-Trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside(23214-92-8)

Contents Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Product Identification Back to Contents 【Product Name】 (1S,3S)-3,5,12-Trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside 【Synonyms】 (85-Cis)-10-Tetrahydro-6,8,11-Trihydroxy-8-(Hydroxyacetyl)-1-methoxy-5,12-Naphthacenedione (8S)-10-((4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione ADM Adriamycin Adriblastin Adriblastina 【CAS】 23214-92-8 【Formula】 C27H29NO11 【Molecular Weight】 543.53 【EINECS】 245-495-6 【RTECS】 AV9800000 【RTECS Class】 Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Natural Product; Primary Irritant 【Merck】 12,3495 【Beilstein/Gmelin】 1445811 Physical and Chemical Properties Back to Contents 【Appearance】 Orange powder. 【Solubility in water】 2% 【Melting Point】 216 【pKa/pKb】 8.33 (pKa) 【Usage】 Medication. First Aid Measures Back to Contents 【Ingestion】 Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended. 【Inhalation】 If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention. 【Skin】 Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. 【Eyes】 Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Handling and Storage Back to Contents 【Storage】 Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. 【Handling】 Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Wash clothing before reuse. Hazards Identification Back to Contents 【Inhalation】 Causes respiratory tract irritation. May cause allergic respiratory tract irritation. Can produce delayed pulmonary edema. 【Skin】 Doxorubicin has irritant properties. Severe ulceration and necrosis may occur from extravasation. 【Eyes】 Causes eye irritation. May cause chemical conjunctivitis. 【Ingestion】 Nausea, vomiting, and diarrhea may occur. Exposure Controls/Personal Protection Back to Contents 【Personal Protection】 Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots. 【Respirators】 Respiratory protection should be an adjunct to and not a substitute for engineering controls.<BR>Organic vapor acid gas canister; done in the open, an area away from drafts and traffic 【Exposure Effects】 Prolonged or repeated exposure may cause adverse reproductive effects. Repeated exposure may cause allergic respiratory reaction (asthma). Effects may be delayed. May cause allergic skin reaction in some individuals. Fire Fighting Measures Back to Contents 【Fire Fighting】 Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire. Accidental Release Measures Back to Contents 【Small spills/leaks】 Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately. Avoid generating dusty conditions. Provide ventilation. Stability and Reactivity Back to Contents 【Stability】 Stable at room temperature in closed containers under normal storage and handling conditions. 【Incompatibilities】 Strong oxidizing agents. 【Decomposition】 Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.

(1S,3S)-3,5,12-Trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside(23214-92-8) More Suppliers Company Name: Shanghai jerryxing Biomedical Technology Co., Ltd Tel: 17721492509; 17721492509 Fax: WebSite: http://www.jrxbiochem.com/ Company Name: Meryer (Shanghai) Chemical Technology Co., Ltd. Tel: 18621169109 Fax: WebSite: https://www.meryer.com/ Company Name: JinYan Chemicals(ShangHai) Co.,Ltd. Tel: 13817811078 Fax: 86-021-50426522,50426273 WebSite: www.jingyan-chemical.com Company Name: Jia Xing Isenchem Co.,Ltd Tel: 0573-85285100 18627885956 Fax: 0573-85285100 WebSite: http://m.approvedhomemanagement.com/ShowSupplierProductsList14265/0.htm Company Name: Chemsky (shanghai) International Co.,Ltd Tel: 021-50135380 Fax: WebSite: www.shchemsky.com Company Name: Shanghai Sunway Pharmaceutical Technology Co., Ltd Tel: 021-51613915-820 13611835272 Fax: 021 51613951 WebSite: http://www.sunwaypharm.com Company Name: Hangzhou Yuhao Chemical Technology Co., Ltd Tel: 0571-82693216 Fax: +86-571-82880190 WebSite: www.chemyuhao.com Company Name: Wuhan Haizheng Industry & Trade Development Co. Ltd Tel: 027-8866 0053/88660577/88660578 Fax: 027-8899 1911 WebSite: m.approvedhomemanagement.com/ShowSupplierProductsList15548/0.htm