Type II TRK?inhibitor 1 NEW
| Price | $1370 | $2780 | $3700 |
| Package | 5mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-01 |
Product Details
| Product Name: Type II TRK?inhibitor 1 | CAS No.: 2937543-72-9 |
| Supply Ability: 10g | Release date: 2025/05/01 |
Product Introduction
Bioactivity
| Name | Type II TRK?inhibitor 1 |
| Description | Type II TRK Inhibitor 1 is a potent inhibitor targeting multiple tropomyosin receptor kinase (TRK) fusion protein variants as well as the wild type. It demonstrates notable antiproliferative effects on Ba/F3 cells expressing CD74-TRKA G667C and ETV6-TRKC G696C, with half-maximal inhibitory concentrations (IC50s) of 6 nM and 1.7 nM, respectively [1]. |
| In vitro | Type II TRK inhibitor 1 (compound 7b) at concentrations ranging from 3.1 to 800 nM and a 2-hour incubation period inhibits the phosphorylation of TRKA, PLCγ1, and ERK [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Keywords | Trkreceptor | Trk receptor |
| Inhibitors Related | Entrectinib | Larotrectinib sulfate | N-Acetyl-5-hydroxytryptamine | Selitrectinib | Sitravatinib | SP600125 | Amitriptyline hydrochloride | 7,8-Dihydroxyflavone | Tepotinib | Diosmetin | GW 441756 | ALE-0540 |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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