天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Welcome to chemicalbook!
+1 (818) 612-2111
RFQ
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >Trospium Nitroso Impurity
Trospium Nitroso Impurity
  • Trospium Nitroso Impurity
  • Trospium Nitroso Impurity
  • Trospium Nitroso Impurity
  • Trospium Nitroso Impurity
  • Trospium Nitroso Impurity

Trospium Nitroso Impurity NEW

Price Get Latest Price
Package 10mg 50mg 100mg
Min. Order: 10mg
Supply Ability: 1000
Update Time: 2025-05-27

Product Details

Product Name: Trospium Nitroso Impurity Min. Order: 10mg
Purity: 99%+ HPLC Supply Ability: 1000
Release date: 2025/05/27

Trospium Nitroso Impurity


Article illustration

WhatsAPP: +86 17320513646
E-mail: anna@molcoo.com


  • Trospium Nitroso Impurity 4

  • Product Information

  • Product Code: T089004

  • English Name: Trospium Nitroso Impurity 4

  • English Alias: (1R,3r,5S)-8-nitroso-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2,2-diphenylacetate

  • CAS No.:[Not Available]

  • Molecular Formula: C??H??N?O?

  • Molecular Weight: 366.41

  • Advantages

  • High Purity: HPLC ≥98.0%, confirmed by NMR and HRMS.

  • Stability: Stable for 12 months at -20℃, with <0.5% degradation in acetonitrile.

  • Regulatory Compliance: Meets EMA guidelines for nitrosamine-containing impurities.

  • Applications

  • Impurity Control: Detects nitrosoester impurities in Trospium formulations via LC-MS.

  • Synthesis Monitoring: Tracks nitroso group transfer during esterification steps.

  • Safety Studies: Supports toxicological evaluation of nitrosoester derivatives.

  • Background Description

  • This impurity arises from nitrosoation of the azabicyclic alcohol followed by esterification. Nitrosoesters pose higher genotoxic risks, requiring rigorous control.
  • Research Status

  • Detection: UPLC-MS/MS with phenyl-hexyl column; LOD: 0.05 ppm.

  • Formation Mechanism: Induced by nitrous acid in esterification media; using anhydrous conditions reduces generation by 75%.

  • Toxicity: Preliminary in vitro studies show mutagenic potential; urgent animal studies prioritized for risk assessment.

NOTE!

We can also customize related analogues and modified peptides including HPLC, MS, 1H-NMR, MS, HPLC, IR, UV, COA, MSDS.
This product is intended for laboratory use only!

WhatsAPP: +86 17320513646
E-mail: anna@molcoo.com


NEW IN STOCK!

The Molcoo Laboratory added drug impurity reference standards, including Baricitinib, Piperazine, Benzylpenicillin, Tranilast and multiple N-Nitroso drug impurities! Now available for immediate delivery! 


Company Profile Introduction

1. Drug standards and drug impurity reference substances: provide more than 20,000 kinds of spot impurity reference substances, with sufficient supply and same-day delivery. We have a professional R&D team and comprehensive quality control testing to ensure product quality and reliability. 2. Customized synthesis of impurities and new molecules: Quickly respond to the customized needs of CDE impurities, stably supply impurities that have established quality standards, and provide customized synthesis services for new compounds in the research and development of innovative drugs. 3. Preparation and separation of unknown impurities: With a professional impurity preparation and separation technical team and SFC preparation and separation instruments, we can solve the problems of impurity preparation in complex projects. 4. Process development of new drug intermediates: provide the supply of new drugs and new molecular impurities, process optimization services, as well as the screening and impurity analysis of commercialization routes. 5. Peptide synthesis: Provide customized peptide synthesis services, and cover all kinds of degradation impurities and process impurities generated in the research and development of peptide drugs. At the same time, it provides comprehensive structural confirmation data and customized testing services.

You may like

Recommended supplier

Product name Price   Suppliers Update time
$0.00/1kg
VIP5Y
Hebei Yanxi Chemical Co., Ltd.
2023-10-07
$30.00/100mg
VIP5Y
TargetMol Chemicals Inc.
2025-05-26
$0.00/10mg
VIP2Y
ShenZhen H&D Pharmaceutical Technology Co., LTD
2025-03-18
INQUIRY