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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Neuronal Signaling>AChR antagonist>Tolterodine tartrate
Tolterodine tartrate
  • Tolterodine tartrate

Tolterodine tartrate NEW

Price $48 $76 $98
Package 25mg 50mg 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-05-02

Product Details

Product Name: Tolterodine tartrate CAS No.: 124937-52-6
Purity: 99.62% Supply Ability: 10g
Release date: 2025/05/02

Product Introduction

Bioactivity

NameTolterodine tartrate
DescriptionTolterodine tartrate (PNU-200583E) is a potent antagonist for muscarinic receptor. It show selectivity for the urinary bladder and salivary glands in vivo.
In vitroTolterodine is a novel muscarinic receptor antagonist for the treatment of symptoms such as overactive bladder and urge incontinence.Tolterodine effectively and competitively inhibited carbamylcholine-induced contractions in guinea pig bladder isolation strips in a concentration-dependent manner.Tolterodine has a high affinity for muscarinic receptors, and its Ki values were 2.7 nM, 1.6 nM, 0.75 nM, 4.8 nM, and 3.3 nM in the bladder, heart,, cortex and human bladder in guinea pigs, respectively. The Ki values of Tolterodine in guinea pig bladder, heart, cerebral cortex, parotid gland and human bladder were 2.7 nM, 1.6 nM, 0.75 nM, 4.8 nM and 3.3 nM, respectively.
In vivoTolterodine is a novel muscarinic receptor antagonist for the treatment of symptoms such as overactive bladder and urge incontinence.Tolterodine effectively and competitively inhibited carbamylcholine-induced contractions in guinea pig bladder isolation strips in a concentration-dependent manner.Tolterodine has a high affinity for muscarinic receptors, and its Ki values were 2.7 nM, 1.6 nM, 0.75 nM, 4.8 nM, and 3.3 nM in the bladder, heart,, cortex and human bladder in guinea pigs, respectively. The Ki values of Tolterodine in guinea pig bladder, heart, cerebral cortex, parotid gland and human bladder were 2.7 nM, 1.6 nM, 0.75 nM, 4.8 nM and 3.3 nM, respectively.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationEthanol : 6 mg/mL (12.62 mM), Sonication is recommended.
H2O : 14 mg/mL (29.44 mM), Sonication is recommended.
DMSO : 88 mg/mL (185.04 mM), Sonication is recommended.
Keywordsurinary | Tolterodine Tartrate | Tolterodine tartrate | Tolterodine | salivary | receptor | Muscarinic acetylcholine receptor | muscarinic | mAChR | Kabi2234 | Kabi 2234 | Inhibitor | inhibit | glands | bladder
Inhibitors RelatedAdiphenine hydrochloride | Nanofin | Forskolin | Pilocarpine Hydrochloride | Clozapine N-Oxide | Pilocarpine nitrate | Urethane | Ribavirin | D-Menthol | Amitriptyline hydrochloride | Choline chloride | Propoxur
Related Compound LibrariesFDA-Approved & Pharmacopeia Drug Library | Failed Clinical Trials Compound Library | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Membrane Protein-targeted Compound Library | Drug-induced Liver Injury (DILI) Compound Library | Anti-Parkinson's Disease Compound Library | Drug Repurposing Compound Library | Inhibitor Library | NO PAINS Compound Library | FDA-Approved Drug Library | Bioactive Compounds Library Max

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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