TC-S 7009 NEW
| Price | $64 | $122 | $247 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: TC-S 7009 | CAS No.: 1422955-31-4 |
| Purity: 99.71% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | TC-S 7009 |
| Description | TC-S 7009 is a potent and selective HIF-2α inhibitor (Kd: 81 nM) with significantly higher affinity for HIF-2α than HIF-1α (Kd >> 5μM). TC-S 7009 disrupts HIF-2α heterodimerization, reduces HIF-2α target gene expression, and diminishes DNA binding activity. |
| In vitro | TC-S 7009 (50 μM) treatment almost fully inhibits hypoxia-induced NFATc2 nuclear translocation. TC-S 7009 (0-100?μM; 72 hours; HPF cells) treatment displays greater inhibition of cell proliferation in hypoxic conditions than that in normoxic conditions [2]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 45.0 mg/mL (145.8 mM), Sonication is recommended. |
| Keywords | TC-S-7009 | TC-S 7009 | TC-S7009 | TCS 7009 | TC S 7009 |
| Inhibitors Related | M1002 | Dapagliflozin | ZINC13466751 | DMOG | PT-2385 | Roxadustat | Hydroxycitric acid tripotassium hydrate | Pantoprazole sodium | Oltipraz | Vadadustat | Acriflavine Hydrochloride | Cinnamaldehyde |
| Related Compound Libraries | Bioactive Compound Library | Inhibitor Library | Bioactive Compounds Library Max |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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