Sophoraflavanone G NEW
| Price | $41 | $96 | $165 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-16 |
Product Details
| Product Name: Sophoraflavanone G | CAS No.: 97938-30-2 |
| Purity: 98.36% | Supply Ability: 10g |
| Release date: 2025/05/16 |
Product Introduction
Bioactivity
| Name | Sophoraflavanone G |
| Description | Sophoraflavanone G (Kushenol F) (Kushenol F), isolated from Sophora flavescens, induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways. |
| In vitro | Sophoraflavanone G (0-100 μM; 24 hours) reduces HL-60 cell viability in a dose-dependent manner and induces apoptosis by activating caspase-3 and caspase-9, downregulating Bcl-2 and Bcl-xL, upregulating Bax, and releasing cytochrome c from mitochondria to cytoplasm, thus promoting apoptosis via the mitochondrially-mediated intrinsic pathway [1]. Additionally, Sophoraflavanone G (0-40 μM; 24 hours) inhibits MDA-MB-231 cell viability with an IC50 of 29.7 μM in a concentration-dependent manner [2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 25 mg/mL (58.89 mM), Sonication is recommended. |
| Keywords | Sophoraflavanone G | Inhibitor | inhibit | HL60 | Apoptosis inducer | Apoptosis | anti-infammatory |
| Inhibitors Related | Stavudine | 5-Fluorouracil | Flubendazole | Cysteamine hydrochloride | Myricetin | Dextran sulfate sodium salt (MW 4500-5500) | Sodium 4-phenylbutyrate | L-Ascorbic acid | L-Glutamic acid | Tributyrin | L-Ascorbic acid sodium salt | Alginic acid |
| Related Compound Libraries | Flavonoid Natural Product Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Selected Plant-Sourced Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Miao medicine Compound Library | Natural Product Library | Natural Product Library for HTS | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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