
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli) NEW
Price | $2730 |
Package | 1mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-05-12 |
Product Details
Product Name: RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli) | Purity: 97% |
Supply Ability: 10g | Release date: 2025/05/12 |
Product Introduction
Bioactivity
Name | RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli) |
Description | CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL is the ligand of nuclear factor (NF)-κB (RANK). When RANKL binds to RANK, it will undergo trimerization and then bind to an adaptor molecule TNF receptor-associated factor 6 (TRAF6). This results in the activation of several downstream signaling cascades, including the NFκB, mitogen-activated protein kinases (MAPK), activating protein 1 (AP-1), and nuclear factor of activated T cells (NFATc1), resulting in the formation of multinucleated bone-resorbing osteoclasts. RANKL is widely expressed in skeletal muscle, thymus, liver, colon, small intestine, adrenal gland, osteoblast, mammary gland epithelial cells, prostate and pancreas. |
Storage | Lyophilized powder: -20~-80°C for 1 year | Shipping with blue ice. |
Keywords | TNFSF-11 | TNFSF 11 | Receptor activator of nuclear factor k-B ligand | CD-254 | CD 254 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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