
Prednisolone valerate acetate NEW
Price | $441 |
Package | 1mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-05-16 |
Product Details
Product Name: Prednisolone valerate acetate | CAS No.: 72064-79-0 |
Purity: 99.93% | Supply Ability: 10g |
Release date: 2025/05/16 |
Product Introduction
Bioactivity
Name | Prednisolone valerate acetate |
Description | Prednisolone valerate acetate (Lidomex) is a corticosteroid hormone and prodrug with anti-inflammatory and immunosuppressive effects, which is converted to the active form of Prednisolone upon administration and acts by targeting the glucocorticoid receptor. |
In vivo | Prednisolone valerate acetate (PVA) was administered to mice via s.c. injection at 0.03–1 mg/kg, with immune responses assessed at 24–48 h and 5–7 d for antibody production. PVA reduced spleen weight and splenic nucleated cell counts, suppressed hemolytic plaque-forming cell (PFC) formation, delayed-type hypersensitivity (DTH), and ConA-induced splenocyte proliferation. Notably, PVA inhibited LPS-induced splenocyte response and IgM antibody production at lower doses than hydrocortisone 17-butyrate (HB), indicating higher potency. Unlike HB and betamethasone 17-valerate (BV), PVA had no effect on PHA-P response. Its suppression of host defense against experimental E. coli infection was weaker than that of HB and BV. [1] |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 4 mg/mL (8.22 mM), Sonication is recommended. |
Keywords | Prednisolone valerate Acetate |
Inhibitors Related | Nimodipine | Hydrocortisone | Mifepristone | Prednisone | Prednisolone acetate | Cortisone | Dexamethasone acetate | Dexamethasone | Betamethasone dipropionate | Prednisone acetate | Desonide | Corticosterone |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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