Pramocaine hydrochloride NEW
| Price | $30 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-28 |
Product Details
| Product Name: Pramocaine hydrochloride | CAS No.: 637-58-1 |
| Purity: 99.57% | Supply Ability: 10g |
| Release date: 2025/04/28 |
Product Introduction
Bioactivity
| Name | Pramocaine hydrochloride |
| Description | Pramocaine hydrochloride (Pramoxine HCl), a topical anesthetic, is served as an antipruritic. |
| In vitro | When administered to canines exhibiting dyspnea (breathing difficulty) and tremors, Pramoxine elicited specific changes in skin temperature at which the activation and suppression of panting and shivering occur. These changes are thought to be mediated by peripheral nerves that control the terminal mechanisms of thermoregulation. In studies on guinea pig ileum, Pramoxine (1.7 mM) demonstrated a lesser reduction in response to Substance P compared to its effects on responses to acetylcholine, BaCl2, and histamine. Pramoxine has been identified as having anesthetic inhibitory potency, with a pKa of 6.4 in guinea pig ileum. |
| In vivo | Pramoxine is frequently used in conjunction with Hydrocortisone, Colloidal oatmeal, Menthol, and Petrolatum. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 75 mg/mL (227.37 mM), Sonication is recommended. |
| Keywords | SodiumChannel | Sodium Channel | Pramoxine Hydrochloride | Pramoxine | Pramocaine Hydrochloride | Pramocaine hydrochloride | Pramocaine | Inhibitor | inhibit |
| Inhibitors Related | Phenytoin sodium | Procaine | Lidocaine Hydrochloride hydrate | Lidocaine | Safinamide | Valproic Acid | Lidocaine hydrochloride | L-Aspartic aicd sodium | Mebeverine hydrochloride | Amitriptyline hydrochloride | Riluzole | Benzocaine |
| Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Sodium Channel Targeted Library | Drug Repurposing Compound Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Cosmetic Ingredient Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Drug Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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