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Postion:Product Catalog >API>Antineoplastic agents>Natural sources of antineoplastic>Podophyllotoxin
Podophyllotoxin
  • Podophyllotoxin

Podophyllotoxin NEW

Price Get Latest Price
Package 1kg
Min. Order: 1kg
Supply Ability: 1000kg
Update Time: 2025-06-03

Product Details

Product Name: Podophyllotoxin CAS No.: 518-28-5
Min. Order: 1kg Purity: 0.99
Supply Ability: 1000kg Release date: 2025/06/03

Introduction to Podophyllotoxin

Definition:
Podophyllotoxin is a natural lignan compound derived from the roots and rhizomes of the Podophyllum species, commonly known as mayapple. It is known for its potent medicinal properties, particularly in cancer treatment and antiviral therapies.

Functions:

· Anticancer: Podophyllotoxin is widely used as a precursor in the synthesis of chemotherapy drugs, such as etoposide and teniposide, which are effective in treating various cancers, including leukemia and lymphoma.

· Antiviral: It exhibits antiviral activity, particularly against human papillomavirus (HPV), making it useful in the treatment of genital warts.

· Cell Cycle Inhibition: Podophyllotoxin disrupts cell division by inhibiting the enzyme topoisomerase II, which is essential for DNA replication in rapidly dividing cancer cells.

Applications:

· Pharmaceuticals: Podophyllotoxin is used in the development of chemotherapy agents and antiviral treatments for HPV-related conditions, such as genital warts.

· Cancer Treatment: It is incorporated into chemotherapy regimens, especially in the treatment of cancers like testicular cancer, small-cell lung cancer, and certain lymphomas.

· Topical Applications: Podophyllotoxin is formulated into topical treatments for warts and other skin-related viral infections.

· Research: Podophyllotoxin is studied in the development of new anticancer and antiviral therapies.


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