LY 456236 hydrochloride NEW
| Price | $48 | $77 | $167 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-18 |
Product Details
| Product Name: LY 456236 hydrochloride | CAS No.: 338736-46-2 |
| Purity: 99.89% | Supply Ability: 10g |
| Release date: 2025/07/18 |
Product Introduction
Bioactivity
| Name | LY 456236 hydrochloride |
| Description | LY 456236 hydrochloride (MPMQ hydrochloride) is an mGlu1 receptor antagonist with an ic50 value of 143 nM. LY456236 has selective, non-competitive and oral activity, and can inhibit the hydrolysis of inositol phosphate with IC50 of 0.145 μM. LY 456236 hydrochloride inhibited EGFR with IC50 of 0.91 μM. |
| In vitro | LY456236 (2 μM; 30 min) reduces the proliferation of DHPG-stimulated OCCM-30 cells.[1] |
| In vivo | LY456236 exhibits anticonvulsant effects in mice (3-100 mg/kg; i.p.; once) and rats (10-60 mg/kg; oral; once).[2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 225.0 mg/mL (708.1 mM), Sonication and heating to 60℃ are recommended. |
| Keywords | MPMQ Hydrochloride | mGluR | LY-456236 Hydrochloride | LY456236 Hydrochloride | LY 456236 Hydrochloride | EGFR |
| Inhibitors Related | Osimertinib | Urethane | Lapatinib | Evans blue | Erlotinib hydrochloride | L-Glutamine | Erlotinib | Neratinib | L-Glutamic acid monosodium salt | Genistein | Gefitinib | O-Phospho-L-serine |
| Related Compound Libraries | Anti-Colorectal Cancer Compound Library | Bioactive Compound Library | Cytokine Inhibitor Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Anti-Breast Cancer Compound Library | Neuroprotective Compound Library | Inhibitor Library | Orally Active Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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