
L-2-Hydroxyglutaric acid disodium NEW
Price | $45 | $83 | $136 |
Package | 10mg | 25mg | 50mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-05-28 |
Product Details
Product Name: L-2-Hydroxyglutaric acid disodium | CAS No.: 63512-50-5 |
Purity: ≥98% | Supply Ability: 10g |
Release date: 2025/05/28 |
Product Introduction
Bioactivity
Name | L-2-Hydroxyglutaric acid disodium |
Description | L-2-Hydroxyglutaric acid disodium ((S)-2-Hydroxyglutaric acid disodium) is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity(Km and Ki of 2.52 mM and 11.13 mM, respectively). |
In vitro | L-2-hydroxyglutarate can effectively inhibit 2-oxoglutarate (2-OG) dependent dioxygenases (2OGDs), including eleven eleven translocation (TET) enzymes [2]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | H2O : 100 mg/mL (520.62 mM), Sonication is recommended. DMSO : < 1 mg/mL (insoluble or slightly soluble) |
Keywords | renal | modifier | MitochondrialMetabolism | Mitochondrial Metabolism | methylation | L-2-Hydroxyglutaric acid disodium | L2Hydroxyglutaric acid disodium | L-2-Hydroxyglutaric acid | L 2 Hydroxyglutaric acid disodium | Inhibitor | inhibit | HistoneDemethylase | Histone Demethylase | histone | epigenetic | demethylases | cancer | 2-Hydroxyglutaric acid disodium | 2-Hydroxyglutaric acid |
Inhibitors Related | Imeglimin hydrochloride | Procaine | Rotenone | α-Lipoic Acid | Tricarballylic acid | Boscalid | α-Lipoic Acid | Lipoic acid | D-Histidine | Nerol | Procaine hydrochloride | Eicosapentaenoic Acid |
Related Compound Libraries | Cuproptosis Compound Library | Methylation Compound Library | Bioactive Compound Library | Epigenetics Compound Library | Kinase Inhibitor Library | Chromatin Modification Compound Library | Inhibitor Library | Mitochondria-Targeted Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Metabolism Disease Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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