JG-231 NEW
| Price | $64 | $178 | $233 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-06-03 |
Product Details
| Product Name: JG-231 | CAS No.: 1627126-59-3 |
| Purity: 99.21% | Supply Ability: 10g |
| Release date: 2025/06/03 |
Product Introduction
Bioactivity
| Name | JG-231 |
| Description | JG-231 is a JG-98 analog with anticancer activity.JG-231 inhibits the MDA-MB-231 xenograft tumor model of triple-negative breast cancer (TNBC).JG-231 inhibits the interaction of Hsp70-BAG3.JG-231 inhibits the MDA-MB-231 xenograft tumor model of triple-negative breast cancer (TNBC). JG-231 inhibits MDA-MB-231 xenograft tumor model of triple negative breast cancer (TNBC). |
| In vivo | JG-231 (2, 4 mg/kg; administered intraperitoneally) effectively suppressed the growth of A375, A375-PLX/R, and Colo829 xenografts in athymic nude mice without causing significant body weight loss. JG231-treated tumors exhibited increased lamin A cleavage and p21CIP1 expression. Moreover, JG231-treated tumors also exhibited increased MEK1/2 phosphorylation.[3] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 1.8 mg/mL (2.9 mM), Sonication is recommended. |
| Keywords | JG-231 | JG231 | JG 231 | HSP70 | AVE8063. | AVE 8063 |
| Inhibitors Related | Ethoxyquin | SNX0723 | Tamoxifen | DN401 | SNX2112 | Teprenone | KRIBB11 | Rifabutin | Palmitic acid | Paeoniflorin | Tamoxifen Citrate | 17-AEP-GA |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Anti-Breast Cancer Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Address: 36 Washington Street, Wellesley Hill, MA
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