FIDAS-3 NEW
| Price | $44 | $71 | $136 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-19 |
Product Details
| Product Name: FIDAS-3 | CAS No.: 1266684-01-8 |
| Purity: 97.75% | Supply Ability: 10g |
| Release date: 2025/05/19 |
Product Introduction
Bioactivity
| Name | FIDAS-3 |
| Description | FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities by effectively competing with S-adenosylmethionine (SAM) for MAT2A binding. |
| In vitro | FIDAS-3 induces the expression of cell cycle inhibitor, p21WAF1/CIP1. FIDAS-3 (10 μM; 36 h) treatment reduces the levels of both S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) in LS174T cells.FIDAS-3 (3 μM; 7 days; LS174T cells) treatment significantly inhibits the proliferation of LS174T cells. FIDAS-3 (3-10 μM) treatment inhibits the expression of c-Myc and cyclinD1 in LS174T CRC cells. |
| In vivo | FIDAS-3 (20 mg/kg;intraperitoneal injection;daily;for one months;C57BL/6J athymic nude mice) treatment significantly inhibits the growth of xenograft tumors. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 90 mg/mL (347.10 mM), Sonication is recommended. |
| Keywords | β-catenin | βcatenin | Wnt/β-catenin | Wnt/betacatenin | Wnt/b-catenin | Wnt | SAM | SAH | S-adenosylmethionine | MethionineAdenosyltransferase(MAT) | MethionineAdenosyltransferase | Methionine S-adenosyltransferase 2A(MAT2A) | Methionine Adenosyltransferase (MAT) | Methionine Adenosyltransferase | MATA2 | MAT2A | MAT | Inhibitor | inhibit | FIDAS-3 | FIDAS3 | FIDAS 3 | CyclinD1 | c-Myc | beta-catenin | betacatenin | bcatenin | anti-proliferation | anti-cancer |
| Inhibitors Related | Urea | PRI-724 | Wnt pathway activator 1 | TNIK-IN-3 | L-quebrachitol | EMT inhibitor-1 | CHIR-99021 | XAV-939 | TNIK-IN-2 | Nefopam hydrochloride | KY-05009 | Bisdemethoxycurcumin |
| Related Compound Libraries | Bioactive Compound Library | Cancer Cell Differentiation Compound Library | Anti-Alzheimer's Disease Compound Library | Epigenetics Compound Library | Anti-Cancer Metabolism Compound Library | Inhibitor Library | Neuroprotective Compound Library | Anti-Fibrosis Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Wnt/Hedgehog/Notch Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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