DS-1040 Tosylate NEW
| Price | $119 | $614 | $798 |
| Package | 2mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-06-09 |
Product Details
| Product Name: DS-1040 Tosylate | CAS No.: 1335138-89-0 |
| Supply Ability: 10g | Release date: 2025/06/09 |
Product Introduction
Bioactivity
| Name | DS-1040 Tosylate |
| Description | DS-1040 Tosylate is a thrombin-activated fibrinolysis inhibitor (TAFIa) inhibitor, also a fibrinolysis enhancer, inhibiting TAFIa and carboxypeptidase N, reducing fibrin clots in the lungs, useful in thromboembolic disease research. |
| In vitro | DS-1040 Tosylate inhibited human carboxypeptidase N (CPN) in vitro with an IC50 of 3.02 mM.[1] |
| In vivo | Methods: DS-1040 Tosylate (0.016, 0.031, 0.063, 0.13, 0.25, 0.50 mg/kg, intravenous injection) was administered to mice with microthrombosis model to investigate the pharmacokinetic changes in vivo. Results: DS-1040 Tosylate increased plasma D-dimer levels in a dose-dependent manner. ED50 and EDmax were 122 and 221nM, respectively. Methods: DS-1040 Tosylate (0.25, 0.5, 1, 2, 4, 8, 16 mg/kg; oral administration) was administered to mice with microthrombosis model to investigate the pharmacokinetic changes in vivo. Results: DS-1040 Tosylate increased plasma D-dimer levels, with EC50 and ECmax values ??of 114 and 231 nmol/L, respectively.[1] |
| Storage | keep away from moisture | store at 4°C | Shipping with blue ice. |
| Solubility Information | H2O : 40 mg/mL (85.91 mM), Sonication is recommended. DMSO : 80 mg/mL (171.82 mM), Sonication is recommended. |
| Keywords | DS 1040 Tosylate |
| Inhibitors Related | Dabigatran Etexilate Mesylate | (S)-(+)-Ibuprofen | Edoxaban | AEBSF hydrochloride | Edoxaban Tosylate Monohydrate | Ozagrel | Menadione | Avatrombopag | Pirodomast | Argatroban | Eltrombopag Olamine | p-Hydroxycinnamic acid |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $48.00/5mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2025-05-26 | |
| $1970.00/25mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2025-04-27 | |
| $100.00/1kg |
VIP3Y
|
Hebei Dangtong Import and export Co LTD
|
2023-03-17 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
INQUIRY