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Postion:Product Catalog >DS-1040 Tosylate
DS-1040 Tosylate
  • DS-1040 Tosylate

DS-1040 Tosylate NEW

Price $119 $614 $798
Package 2mg 25mg 50mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-06-09

Product Details

Product Name: DS-1040 Tosylate CAS No.: 1335138-89-0
Supply Ability: 10g Release date: 2025/06/09

Product Introduction

Bioactivity

NameDS-1040 Tosylate
DescriptionDS-1040 Tosylate is a thrombin-activated fibrinolysis inhibitor (TAFIa) inhibitor, also a fibrinolysis enhancer, inhibiting TAFIa and carboxypeptidase N, reducing fibrin clots in the lungs, useful in thromboembolic disease research.
In vitroDS-1040 Tosylate inhibited human carboxypeptidase N (CPN) in vitro with an IC50 of 3.02 mM.[1]
In vivoMethods: DS-1040 Tosylate (0.016, 0.031, 0.063, 0.13, 0.25, 0.50 mg/kg, intravenous injection) was administered to mice with microthrombosis model to investigate the pharmacokinetic changes in vivo. Results: DS-1040 Tosylate increased plasma D-dimer levels in a dose-dependent manner. ED50 and EDmax were 122 and 221nM, respectively. Methods: DS-1040 Tosylate (0.25, 0.5, 1, 2, 4, 8, 16 mg/kg; oral administration) was administered to mice with microthrombosis model to investigate the pharmacokinetic changes in vivo. Results: DS-1040 Tosylate increased plasma D-dimer levels, with EC50 and ECmax values ??of 114 and 231 nmol/L, respectively.[1]
Storagekeep away from moisture | store at 4°C | Shipping with blue ice.
Solubility InformationH2O : 40 mg/mL (85.91 mM), Sonication is recommended.
DMSO : 80 mg/mL (171.82 mM), Sonication is recommended.
KeywordsDS 1040 Tosylate
Inhibitors RelatedDabigatran Etexilate Mesylate | (S)-(+)-Ibuprofen | Edoxaban | AEBSF hydrochloride | Edoxaban Tosylate Monohydrate | Ozagrel | Menadione | Avatrombopag | Pirodomast | Argatroban | Eltrombopag Olamine | p-Hydroxycinnamic acid

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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