Direct Blue 1 NEW
| Price | $42 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-02 |
Product Details
| Product Name: Direct Blue 1 | CAS No.: 2610-05-1 |
| Purity: 50% | Supply Ability: 10g |
| Release date: 2025/07/02 |
Product Introduction
Bioactivity
| Name | Direct Blue 1 |
| Description | Direct Blue 1 (Pontamine sky blue), a counterstain for background autofluorescence in immunofluorescence histochemistry, structurally resembles glutamate and operates as a potent, competitive VGLUT inhibitor, not impacting plasma membrane transporters. This compound stands out as the inaugural small molecule PrP ligand to inhibit Aβ binding. |
| In vitro | Instructions I. Dissolve and prepare dye solution 1. Solution preparation: Dissolve Direct Blue 1 in water. Common dye concentrations range from 0.1% to 1% (w/v). The specific concentration is adjusted according to experimental needs. For example, when the dye solution concentration is 0.5%, 5 mg of dye is usually mixed with 1 mL of solvent. 2. Staining process: 1) Prepare samples: Prepare samples to be stained (such as textiles, proteins, cells, etc.) according to the type of experiment. 2) Staining solution: Add the prepared Direct Blue 1 solution to the sample. The staining time is usually 20 to 60 minutes, depending on the staining intensity requirements. 3) pH value: During staining, the pH value of the dye solution usually needs to be kept at acidic or neutral (pH 4-7). If the sample is sensitive to pH, precise pH control may be required. 4) Washing: After staining, wash with water or an appropriate buffer to remove unbound dye until the sample no longer releases dye. II. Applications 1. Protein or DNA staining: Direct Blue 1 can be used for staining in gel electrophoresis, especially for staining proteins and other biomacromolecules. 2. Cell staining: In cell biology experiments, Direct Blue 1 is often used for cell staining to facilitate observation of cell morphology or counting under a microscope. 3. Surface adsorption experiments: Because Direct Blue 1 can strongly adsorb to different surfaces (such as fibers, membranes or cell surfaces), it can also be used for surface adsorption or adsorption experiments. |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : Slightly soluble |
| Keywords | Inhibitor | inhibit | Glutamate Transporters | glutamate | Direct Blue-1 | Direct Blue1 | Direct Blue 1 | counterstain | autofluorescence |
| Inhibitors Related | IDRA-21 | Urethane | Decanoic Acid | Xanthurenic Acid | L-Cysteic acid monohydrate | DCB | Evans blue | L-Glutamine | L-Glutamic acid monosodium salt | Piracetam | O-Phospho-L-serine | Memantine hydrochloride |
| Related Compound Libraries | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Neurotransmitter Receptor Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Human Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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