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Postion:Product Catalog >Compound 3344 hydrochloride
Compound 3344 hydrochloride
  • Compound 3344 hydrochloride

Compound 3344 hydrochloride NEW

Price $146 $298 $448
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-04-27

Product Details

Product Name: Compound 3344 hydrochloride Purity: 99.89%
Supply Ability: 10g Release date: 2025/04/27

Product Introduction

Bioactivity

NameCompound 3344 hydrochloride
DescriptionCompound 3344 hydrochloride is an inhibitor of KRAS-effector interactions,with an affnity of 126nM.
In vitroIn vitro competition studies of 3344 hydrochloride binding to KRAS-G12V in waterLOGSY NMR show the anti-RAS scFv inhibits 3344 hydrochloride binding to KRAS. In view of the in vitro inhibition by the anti-RAS scFv of 3344 hydrochloride binding to RASand because the iDAb RAS interferes with BRET signal in cells, 3344 hydrochloride was used for validation of the BRET2 toolbox for RAS-effector PPI inhibitors.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 60 mg/mL (140.53 mM), Sonication is recommended.
KeywordsKRAS | Compound 3344 Hydrochloride | Compound 3344 hydrochloride | 2368246-78-8 free base | 2368246-78-8
Inhibitors RelatedAdagrasib | (S)-AMG-510 | BI-2493 | ARS-1323 | ARS-1323-alkyne | Kras4B G12D-IN-1 | BI-3406 | MRTX1133 | MRTX-1257 | Sotorasib | RMC-7977 | GNE-9815
Related Compound LibrariesReprogramming Compound Library | Anti-Pancreatic Cancer Compound Library | Pain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Anti-Cancer Metabolism Compound Library | Inhibitor Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Liver Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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