Bacoside A3 NEW
| Price | $140 | $357 |
| Package | 1mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-27 |
Product Details
| Product Name: Bacoside A3 | CAS No.: 157408-08-7 |
| Purity: 99.67% | Supply Ability: 10g |
| Release date: 2025/05/27 |
Product Introduction
Bioactivity
| Name | Bacoside A3 |
| Description | Bacoside A3 is one of the components of Bacopa monnieri (L.) Wettst. bacoside A with antioxidant potential. Bacoside A3 shows comparatively higher neuroprotective response analysed as higher cell viability and decreased intracellular ROS. |
| In vitro | The cytoprotective effects of individual bacoside A components were evaluated towards oxidative stressed neuronal cells. Bacoside A was screened for neuronal cell viability (MTT assay) and change in intracellular reactive oxygen species (ROS), anti-apoptotic properties and mitochondrial membrane potential (MMP) using fluorescence microscopy. Different bacoside A components showed decrease in N2a cell viability below 100 (%) after bacoside A concentration of 0.4 mg/ml. Further, cytoprotective effect of optimized dose of bacoside A was analysed for alleviating oxidative stressed, apoptosis and MMP in H2 O2 stressed neuronal cells. Results showed increase in MMP, and decrease in apoptotic induction, without much change in nuclear integrity in stressed neuronal cells. Results showed Bacoside A3 and bacopaside II have comparatively higher cytoprotective ability whilst isomer of bacopasponin C, bacopasaponin C and mixture showed comparatively less response[1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 60 mg/mL (64.58 mM), Sonication is recommended. |
| Keywords | ROS | P-gp | Pgp | Inhibitor | inhibit | Bacoside A-3 | Bacoside A3 | Bacoside A 3 | ATPase |
| Inhibitors Related | Acetylcysteine | Cyanidin | Sodium oleate | Polyoxyethylene stearate | Inosine | Tempol | Lycopene | Ethyl cinnamate | Revaprazan hydrochloride | Oleic acid | β-Carotene | Cinchonine |
| Related Compound Libraries | Terpene Natural Product Library | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Rare Natural Product Library | Membrane Protein-targeted Compound Library | Selected Plant-Sourced Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library | Natural Product Library for HTS | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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