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Postion:Product Catalog >4-hydroperoxy cyclophosphamide
4-hydroperoxy cyclophosphamide
  • 4-hydroperoxy cyclophosphamide

4-hydroperoxy cyclophosphamide NEW

Price $230
Package 1mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-04

Product Details

Product Name: 4-hydroperoxy cyclophosphamide CAS No.: 39800-16-3
Purity: 98% Supply Ability: 10g
Release date: 2024/11/04

Product Introduction

Bioactivity

名稱4-hydroperoxy cyclophosphamide
描述4-hydroperoxy cyclophosphamide (4-OOH-CY) is an active metabolite of Cyclophosphamide that induces hepatotoxicity.4-Hydroperoxy cyclophosphamide increases levels of glutaminase and aspartate aminotransferase, enhances inflammatory factors and oxidative markers, and Inhibits oxidoreductase activity.4-Hydroperoxy cyclophosphamide is used in the study of cancer and autoimmune diseases.
體外活性4-hydroperoxy cyclophosphamide mediates caspase-independent T cell apoptosis through oxidative stress-induced nuclear relocalization of mitochondrial apoptotic factors AIF and EndoG. [1] The combination of 1 μg/mL 4-hydroperoxy cyclophosphamide and methotrexate inhibited IL-6/sil-6r-induced RANKL expression in fibroblast-like synoviocytes through inhibition of JAK2/STAT3 and p38MAPK signaling pathways. [2]
體內(nèi)活性Intraperitoneal injection of 200 mg/kg 4-hydroperoxy cyclophosphamide resulted in caspase-independent T and B cell death in mice. [1]
存儲(chǔ)條件store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度Dichloromethane : <1 mg/mL(insoluble or slightly soluble)
DMSO : 30 mg/mL(102.36 mM), Sonication is recommended.
Chloroform : <1 mg/mL(insoluble or slightly soluble)
關(guān)鍵字4 hydroperoxy Cyclophosphamide | 4hydroperoxy Cyclophosphamide | 4-hydroperoxy Cyclophosphamide
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Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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