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Postion:Product Catalog >Pharmaceutical intermediates>Heterocyclic compound>Pyrimidines>Methylpyrimidine>2,4-Dichloro-5-trifluoromethyl-pyrimidine
2,4-Dichloro-5-trifluoromethyl-pyrimidine
  • 2,4-Dichloro-5-trifluoromethyl-pyrimidine

2,4-Dichloro-5-trifluoromethyl-pyrimidine NEW

Price Get Latest Price
Package 50kg 200kg
Min. Order: 100kg
Supply Ability: 20 tons
Update Time: 2025-04-02

Product Details

Product Name: 2,4-Dichloro-5-trifluoromethyl-pyrimidine CAS No.: 3932-97-6
EC-No.: 609-648-4 Min. Order: 100kg
Purity: 0.99 Supply Ability: 20 tons
Release date: 2025/04/02

2,4-Dichloro-5-(trifluoromethyl)pyrimidine CAS 3932-97-6 | Core Supplier of Highly Reactive Fluorinated Pyrimidine Intermediates

[Core Keywords]: 2,4-Dichloro-5-(trifluoromethyl)pyrimidine Supplier, CAS 3932-97-6, Fluorinated Pyrimidine Pharmaceutical Intermediates, Custom Synthesis of Agrochemicals

Product Basic Information

Chemical Name: 2,4-Dichloro-5-(trifluoromethyl)pyrimidine
CAS Number: 3932-97-6 (Title-Level Keyword Enhancement)
Molecular Formula: C5HCl2F3N2
Appearance: White to off-white crystalline solid
Purity: ≥99.0% (HPLC, Pharmaceutical Intermediate Grade)

Key Physical and Chemical Properties (Structured Data Optimization)


PropertyParameter Value
Molecular Weight222.98 g/mol
Melting Point65-68°C (determined by dynamic DSC)
Boiling Point (5 mmHg)120-125°C (before sublimation)
Density (25°C)1.62 g/cm3
SolubilitySoluble in acetone, DCM; slightly soluble in ethanol; insoluble in water
Storage ConditionsStore in a cool, dark place, sealed, and dried at -20°C


Upstream and Downstream Industry Chain Integration

? Upstream Raw Materials and Key Intermediates: 5-(Trifluoromethyl)pyrimidine-2,4-diol, Phosphorus Oxychloride (POCl?)
Process Optimization: Stepwise Chlorination Technology (Selectivity >98%, Byproducts <0.3%)

? Downstream Application Expansion

  • Antiviral Drugs: Key fragment for HCV protease inhibitors

  • Agrochemical Herbicides: Precursor for triketone HPPD inhibitors

  • Electronic Materials: Modifier monomer for OLED electron transport layers

  • CRO/CDMO: High-throughput synthesis of kinase inhibitor molecular libraries

Industry Solutions and Technical Advantages


Application AreaTypical ScenarioTechnical Advantages
Antiinfective DrugsCOVID-19 main protease (3CLpro) inhibitorsChlorine substitution site activity >95% (verified by LC-MS)
Agrochemical FormulationsStructural modification of novel broad-spectrum herbicidesLight resistance (stability >90% under UV 300nm)
Optoelectronic MaterialsSynthesis of organic semiconductor hole transport materialsPurity ≥99.9% (zone melting refinement process)
Molecular ProbesLinker building blocks for targeted protein degradation (PROTAC)Precise regulation of fluorine atom electronic effects >98%


SEO Keyword Matrix

Core Words Layout: "2,4-Dichloro-5-(trifluoromethyl)pyrimidine Price", "CAS 3932-97-6 Technical Parameters", "Highly Reactive Fluorinated Pyrimidine Supplier"

Long-Tail Keyword Combinations: "Custom Synthesis of Antiviral Drug Intermediates", "Producer of HPPD Inhibitor Pyrimidine Raw Materials", "Pharmaceutical Grade 3932-97-6 Manufacturer"

Quality System and Service Commitment

cGMP Compliant Production: Complies with ICH Q11 Active Pharmaceutical Ingredient (API) Starting Material Standards
Customized Services: Supports orders from gram-scale to hundred-kilogram scale (MOQ 50g)
Analysis Report: Provides a full set of documents including HPLC, 19F NMR, and elemental analysis
Global Logistics: UN-standard packaging (moisture-proof aluminum foil bags with desiccants)



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Company Profile Introduction

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  • Since: 2004-04-13
  • Address: No. 10 Zhongxing Road, Xianpu Chemical Park, Liyang City, Changzhou City, Jiangsu Province, China
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