
2,4-Dichloro-5-trifluoromethyl-pyrimidine NEW
Price | Get Latest Price | |
Package | 50kg | 200kg |
Min. Order: | 100kg |
Supply Ability: | 20 tons |
Update Time: | 2025-04-02 |
Product Details
Product Name: 2,4-Dichloro-5-trifluoromethyl-pyrimidine | CAS No.: 3932-97-6 |
EC-No.: 609-648-4 | Min. Order: 100kg |
Purity: 0.99 | Supply Ability: 20 tons |
Release date: 2025/04/02 |
2,4-Dichloro-5-(trifluoromethyl)pyrimidine CAS 3932-97-6 | Core Supplier of Highly Reactive Fluorinated Pyrimidine Intermediates
[Core Keywords]: 2,4-Dichloro-5-(trifluoromethyl)pyrimidine Supplier, CAS 3932-97-6, Fluorinated Pyrimidine Pharmaceutical Intermediates, Custom Synthesis of Agrochemicals
Product Basic Information
Chemical Name: 2,4-Dichloro-5-(trifluoromethyl)pyrimidine
CAS Number: 3932-97-6 (Title-Level Keyword Enhancement)
Molecular Formula: C5HCl2F3N2
Appearance: White to off-white crystalline solid
Purity: ≥99.0% (HPLC, Pharmaceutical Intermediate Grade)
Key Physical and Chemical Properties (Structured Data Optimization)
Property | Parameter Value |
---|---|
Molecular Weight | 222.98 g/mol |
Melting Point | 65-68°C (determined by dynamic DSC) |
Boiling Point (5 mmHg) | 120-125°C (before sublimation) |
Density (25°C) | 1.62 g/cm3 |
Solubility | Soluble in acetone, DCM; slightly soluble in ethanol; insoluble in water |
Storage Conditions | Store in a cool, dark place, sealed, and dried at -20°C |
Upstream and Downstream Industry Chain Integration
? Upstream Raw Materials and Key Intermediates: 5-(Trifluoromethyl)pyrimidine-2,4-diol, Phosphorus Oxychloride (POCl?)
Process Optimization: Stepwise Chlorination Technology (Selectivity >98%, Byproducts <0.3%)
? Downstream Application Expansion
Antiviral Drugs: Key fragment for HCV protease inhibitors
Agrochemical Herbicides: Precursor for triketone HPPD inhibitors
Electronic Materials: Modifier monomer for OLED electron transport layers
CRO/CDMO: High-throughput synthesis of kinase inhibitor molecular libraries
Industry Solutions and Technical Advantages
Application Area | Typical Scenario | Technical Advantages |
---|---|---|
Antiinfective Drugs | COVID-19 main protease (3CLpro) inhibitors | Chlorine substitution site activity >95% (verified by LC-MS) |
Agrochemical Formulations | Structural modification of novel broad-spectrum herbicides | Light resistance (stability >90% under UV 300nm) |
Optoelectronic Materials | Synthesis of organic semiconductor hole transport materials | Purity ≥99.9% (zone melting refinement process) |
Molecular Probes | Linker building blocks for targeted protein degradation (PROTAC) | Precise regulation of fluorine atom electronic effects >98% |
SEO Keyword Matrix
Core Words Layout: "2,4-Dichloro-5-(trifluoromethyl)pyrimidine Price", "CAS 3932-97-6 Technical Parameters", "Highly Reactive Fluorinated Pyrimidine Supplier"
Long-Tail Keyword Combinations: "Custom Synthesis of Antiviral Drug Intermediates", "Producer of HPPD Inhibitor Pyrimidine Raw Materials", "Pharmaceutical Grade 3932-97-6 Manufacturer"
Quality System and Service Commitment
? cGMP Compliant Production: Complies with ICH Q11 Active Pharmaceutical Ingredient (API) Starting Material Standards
? Customized Services: Supports orders from gram-scale to hundred-kilogram scale (MOQ 50g)
? Analysis Report: Provides a full set of documents including HPLC, 19F NMR, and elemental analysis
? Global Logistics: UN-standard packaging (moisture-proof aluminum foil bags with desiccants)
Company Profile Introduction
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- Since: 2004-04-13
- Address: No. 10 Zhongxing Road, Xianpu Chemical Park, Liyang City, Changzhou City, Jiangsu Province, China