
2-Deoxy-D-ribose NEW
Price | Get Latest Price | |
Package | 1kg | 25kg |
Min. Order: | 1kg |
Supply Ability: | 1000kg |
Update Time: | 2025-05-21 |
Product Details
Product Name: 2-Deoxy-D-ribose | CAS No.: 533-67-5 |
EC-No.: 208-573-0 | Min. Order: 1kg |
Purity: 98% | Supply Ability: 1000kg |
Release date: 2025/05/21 |
2-Deoxy-D-ribose is a pentose sugar integral to the structure of DNA. Here's a detailed breakdown:
Chemical Structure:
It is a derivative of D-ribose, where the hydroxyl (-OH) group at the 2' position (in cyclic form) is replaced by a hydrogen atom. This absence of oxygen at the 2' carbon distinguishes it from ribose, the sugar in RNA.
Linear Form: A five-carbon chain (pentose) with hydroxyl groups on carbons 1, 3, and 4. Carbon 2 has two hydrogens instead of a hydroxyl group.
Cyclic Form: Forms a five-membered furanose ring (oxygen in the ring from C1's carbonyl group). The 2' position lacks a hydroxyl group, reducing reactivity.
Configuration:
The D- prefix indicates the configuration of the highest-numbered chiral carbon (C4 in deoxyribose). In the Fischer projection, the hydroxyl on C4 is on the right, mirroring naturally occurring sugars.
Role in DNA:
Backbone Stability: The missing 2' hydroxyl group makes DNA less prone to hydrolysis compared to RNA, enhancing its stability for long-term genetic storage.
Phosphodiester Bonds: Connects nucleotides via bonds between the 3' hydroxyl of one deoxyribose and the 5' phosphate of another, forming DNA's sugar-phosphate backbone.
Biological Significance:
Critical for DNA's double-helix structure. The deoxyribose-phosphate backbone supports base pairing (A-T, C-G), enabling genetic encoding and replication.
Summary: 2-Deoxy-D-ribose is the DNA sugar backbone component, characterized by a missing 2' hydroxyl group. This structural feature underpins DNA's chemical stability and its role as the hereditary material in organisms.
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- Since: 2006-04-03
- Address: Room 2015, No.2 Building Kaixin Mansion, No.107 Jinqiao Ave, Wuhan, China
+86-13986145403
info@fortunachem.com