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Postion:Product Catalog >Pharmaceutical intermediates>Bulk Drug Intermediates>(1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride
(1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride
  • (1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride
  • (1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride
  • (1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride
  • (1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride

(1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride

Price Get Latest Price
Package 25kg
Min. Order: 0.001kg
Supply Ability: 1000000MT
Update Time: 2025-06-11

Product Details

Product Name: (1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride CAS No.: 171752-68-4
EC-No.: 1592732-453-0 Min. Order: 0.001kg
Purity: 99.99% Supply Ability: 1000000MT
Release date: 2025/06/11

Chemical Properties

Melting point239-241 °C
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMSO (Slightly, Sonicated), Methanol (Slightly)
form Solid
color Off-White to Pale Yellow
StabilityHygroscopic
InChIInChI=1/C20H18N2O4.ClH/c1-24-20(23)15-9-13-12-4-2-3-5-14(12)21-19(13)18(22-15)11-6-7-16-17(8-11)26-10-25-16;/h2-8,15,18,21-22H,9-10H2,1H3;1H/t15-,18-;/s3
InChIKeyROYJOKDTCKPQHK-QHWQFTOMNA-N
SMILESC12[C@@H](C3=CC=C4OCOC4=C3)N[C@H](CC=1C1C(=CC=CC=1)N2)C(OC)=O.Cl |&1:1,12,r|

Usage And Synthesis

Preparation
D-tryptophan methyl ester hydrochloride and piperonal chloride dissolved in redistilled tetrahydrofuran and then added trifluoroacetic acid. Stir the reaction at 30 ° C for 10 h under the protection of nitrogen. Add sodium triacetoxyborohydride and continue the reaction for 3 hours. After the reaction is monitored by a TLC plate, the reaction solution is concentrated to about 10 mL, deionized water is added, and extracted with ethyl acetate twice. Saturated sodium chloride was washed twice, and dried under reduced pressure to obtain (1R,3R)-Methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate hydrochloride. The yield was 86.95%, the purity was 98.76%.
Article illustration


Company Profile Introduction

Anhuyan (Hainan) Biotechnology Co., LTD, factory was founded in 2014 and has been engaged in the research and development and production of fine chemical raw materials and chemical reagents for a long time. The company has strong technical strength. Its products sell well all over the country and are exported abroad. It is deeply trusted by users and is rated as a high-tech enterprise in Hubei province. After years of development, it has now formed a variety of product series, biological buffer series; Amino acid and amino acid derivatives series; Natural cosmetic raw material Series; Chemical reagent series; Pharmaceutical and chemical raw materials and intermediates, etc. We are committed to the development of high-quality products, which have been widely used in daily chemicals, food additives, textile additives, lubricating oil, resin, pesticide, medicine and chemical industry and other industries. Products include: Condo, CAPS,TRIS, dehydrorosin, polypropylene amine hydrochloride, 5,6-dihydroxyindole, chromium acetylpyruvate, tetraacetyl ribose, phosphomolybdic acid, molybdenum acid, 4-aminoantipyrine, dihydrochalcone, dithiosulfontanol (DTT),5-isoquinoline sulfonic acid, 6-benzylaminopyrine, isopropylate, camphoroquinone, silk fibroin, docurate sodium, etc. New loyalty customers are welcome to come for consultation and purchase. Our company was renamed Hubei Yiling biotechnology LTD in 2014. It is a comprehensive high-tech modern enterprise integrating research and development, production and sales. Its sales company and research and development center are located in Guanggu biological City Medical Park, Wuhan city, Hubei Province. The company covers an area of 66279.6 sqm and has 2 production bases and 2 modern scientific research centers. The company has the international leading technical level, and has a group of professional scientific research personnel engaged in this industry. The academic leaders have a doctor's degree or above and have many years of

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