(2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid manufacturers
- Boc-Val-Cit-OH
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- $0.00 / 25kg
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2025-05-08
- CAS:870487-08-4
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 1000kg
- Boc-Val-Cit
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- $0.00 / 25g
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2024-03-29
- CAS:870487-08-4
- Min. Order: 25g
- Purity: >95.00%
- Supply Ability: 25g
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| (2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid Basic information |
| (2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid Chemical Properties |
Boiling point | 624.8±55.0 °C(Predicted) | density | 1.183±0.06 g/cm3(Predicted) | solubility | Soluble in DMSO | pka | 3.44±0.10(Predicted) | form | Solid | color | White to off-white |
| (2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid Usage And Synthesis |
Description | Boc-Val-Cit is a cleavable ADC linker. The Val-Cit will specifically be cleaved by Cathepsin B. Boc group can be removed under acidic condition. | Uses | Boc-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | IC 50 | Protease Cleavable Linker; Cleavable Linker | References | [1] Kevin HAMBLETT, et al. Anti-her2 biparatopic antibody-drug conjugates and methods of use. WO2019173911A1. |
| (2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanamido]-5-(carbamoylamino)pentanoic acid Preparation Products And Raw materials |
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