|
|
| | 1,3-Dioxo-2-isoindolineaceticacid Basic information |
| Product Name: | 1,3-Dioxo-2-isoindolineaceticacid | | Synonyms: | N-(1,3-Dihydro-1,3-dioxoisobenzofuran-4-yl)acetamide;AcetaMide, N-(1,3-dihydro-1,3-dioxo-4-isobenzofuranyl)-;3-AcetylaMino-phthalsaeure-anhydrid;1,3-Dioxo-2-isoindolineaceticacid CAS:6296-53-3;N-(1,3-Dioxo-1,3-dihydro-2-benzofuran-4-yl)acetaMide;NSC 16261;NSC 17048;N-(1,3-Dioxo-4-isobenzofuranyl)acetaMide | | CAS: | 6296-53-3 | | MF: | C10H7NO4 | | MW: | 205.17 | | EINECS: | 808-040-8 | | Product Categories: | | | Mol File: | 6296-53-3.mol |  |
| | 1,3-Dioxo-2-isoindolineaceticacid Chemical Properties |
| Melting point | 185-186℃ | | Boiling point | 489.1±28.0 °C(Predicted) | | density | 1.512±0.06 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Chloroform (Slightly, Sonicated), Ethyl Acetate (Slightly, Sonicated), Methanol | | form | Solid | | pka | 13.81±0.20(Predicted) | | color | Off-White to Pale Yellow | | Stability: | Moisture Sensitive |
| | 1,3-Dioxo-2-isoindolineaceticacid Usage And Synthesis |
| Uses | 3-Acetylaminophthalic Anhydride is used in the synthesis of Apremilast, a potent phosphodiesterase 4 and tumor necrosis Factor-α inhibitor used in the treatment of psoriatic arthritis. Also a reagent in the preparation of Tillivalline. Apremilast Impurity 2 |
| | 1,3-Dioxo-2-isoindolineaceticacid Preparation Products And Raw materials |
|