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1-Oleoyl Lysophosphatidic Acid

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Products Intro: Product Name:1-Oleoyl Lysophosphatidic Acid
CAS:65528-98-5
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Products Intro: Product Name:1-Oleoyl lysophosphatidic acid
CAS:65528-98-5
Purity:>=95%，10mg/ml in ethanol Package:$28.9/1mg;$129.9/5mg;$228.9/10mg;Bulk package Remarks:95%，10mg/ml in ethanol
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Products Intro: Product Name:1-Oleoyl lysophosphatidic acid
CAS:65528-98-5
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Products Intro: Product Name:1-Oleoyl lysophosphatidic acid
CAS:65528-98-5
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Products Intro: Product Name:1-Oleoyl lysophosphatidic acid
CAS:65528-98-5
Purity:95% Package:1G;10G;100G Remarks:1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase

1-Oleoyl Lysophosphatidic Acid manufacturers
1-Oleoyl Lysophosphatidic Acid Basic information
Product Name:1-Oleoyl Lysophosphatidic Acid
Synonyms:1-Oleoyl Lysophosphatidic Acid Exclusive;9-Octadecenoic acid (9Z)-, (2R)-2-hydroxy-3-(phosphonooxy)propyl ester;WRGQSWVCFNIUNZ-GDCKJWNLSA-N
CAS:65528-98-5
MF:C21H41O7P
MW:436.52
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Mol File:65528-98-5.mol
1-Oleoyl Lysophosphatidic Acid Structure
1-Oleoyl Lysophosphatidic Acid Chemical Properties
Boiling point 581.5±60.0 °C(Predicted)
density 1.103±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 2 mg/ml; DMSO: 2.5 mg/ml; Ethanol: 25 mg/ml; PBS (pH 7.2): 3 mg/ml
form Liquid
pka1.82±0.10(Predicted)
color Colorless to light yellow
Safety Information
MSDS Information
1-Oleoyl Lysophosphatidic Acid Usage And Synthesis
Uses1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) is an abundant lysophosphatidic acid (LPA) species with high biological activity due to its strong affinity for the LPA receptors. 1-Oleoyl lysophosphatidic acid is commonly used in most laboratories as a reagent for LPA receptor activation[1]. 1-Oleoyl lysophosphatidic acid increases SRE-driven β-galactosidase activity[2].
DefinitionChEBI: 1-oleoyl-sn-glycerol 3-phosphate is a 1-acyl-sn-glycerol 3-phosphate having oleoyl as the 1-O-acyl group. It is a conjugate acid of a 1-oleoyl-sn-glycero-3-phosphate(2-).
in vivo

1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) (0.4-2 μg; i.c.v.; 9-week-old male Wistar rats) induces anxiety-like responses in the elevated plus maze (EPM) under novelty conditions[1].

Animal Model:9-week-old male Wistar rats[1]
Dosage:0.4-2 μg
Administration:I.c.v.
Result:Reduced open arm exploration under novelty conditions and had no effect under habituated conditions in the EPM.
References[1] Castilla-Ortega E, et al. 1-Oleoyl lysophosphatidic acid: a new mediator of emotional behavior in rats. PLoS One. 2014;9(1):e85348. Published 2014 Jan 7. DOI:10.1371/journal.pone.0085348
[2] Perkins LM, et al. Activation of serum response element-regulated genes by lysophosphatidic acid. Nucleic Acids Res. 1994;22(3):450-452. DOI:10.1093/nar/22.3.450
1-Oleoyl Lysophosphatidic Acid Preparation Products And Raw materials
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