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| | 20R-Camptothecin Basic information |
| Product Name: | 20R-Camptothecin | | Synonyms: | (R)-(-)-Camptothecin;(R)-(-)-Camptothecine;(R)-4-Ethyl-4-hydroxy-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;(R)-Camptothecin;20R-Camptothecin;(4R)-4β-Ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;Camptothecin Impurity 6;Irinotecan Impurity 42 | | CAS: | 110351-92-3 | | MF: | C20H16N2O4 | | MW: | 348.35 | | EINECS: | | | Product Categories: | Pharmaceuticals;Intermediates & Fine Chemicals;Inhibitors;Heterocycles;Chiral Reagents | | Mol File: | 110351-92-3.mol |  |
| | 20R-Camptothecin Chemical Properties |
| Boiling point | 757.0±60.0 °C(Predicted) | | density | 1.51±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 11.24±0.20(Predicted) |
| | 20R-Camptothecin Usage And Synthesis |
| Uses | Antitumor alkaloid. Binds irreversible to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. A cytotoxic antitumor agent. |
| | 20R-Camptothecin Preparation Products And Raw materials |
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