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183321-86-0 Basic information More..
Product Name:OSI-420
Synonyms:CP 373420;OSI-420 (free base);Erlotinib O-DesMethyl Metabolite;Erlotinib iMpurity H;Desmethyl Erlotinib (CP-473420, OSI-420);6-O-Desmethyl Erlotinib 1;2-((4-((3-ethynylphenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethan-1-ol;2-((4-((3-Ethynylphenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethanol
CAS:183321-86-0
MF:C21H21N3O4
MW:379.41
EINECS:
Mol File:183321-86-0.mol
183321-86-0

Use

OSI-420 (Desmethyl Erlotinib,CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells.

OSI-420 manufacturers

  • Desmethyl Erlotinib
  • US $48.00-117.00 / mg
  • 2025-04-28
  • CAS:183321-86-0
  • Min. Order:
  • Purity: 98.62%
  • Supply Ability: 10g
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Products Intro: Product Name:2-({4-[(3-Ethynylphenyl)amino]-7-(2-methoxyethoxy)-6-quinazolinyl }oxy)ethanol
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