KD 5170
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- $34 - $1029
- Product name: KD 5170
- CAS: 940943-37-3
- MF: C20H25N3O5S2
- MW: 451.56
- EINECS:
- MDL Number:
- Synonyms:KD 5170;S-(2-(6-(4-(3-(DiMethylaMino)propoxy)phenylsulfonaMido)pyridin-3-yl)-2-oxoethyl) ethanethioate;KD5170; KD-5170;S-(2-{6-[({4-[3-(dimethylamino)propoxy]phenyl}sulfonyl)amino]-3-p Yridinyl}-2-oxoethyl) Ethanethioate;Ethanethioic acid, S-[2-[6-[[[4-[3-(dimethylamino)propoxy]phenyl]sulfonyl]amino]-3-pyridinyl]-2-oxoethyl] ester;KD5170, HDAC inhibitor
19 prices
Selected condition:
Brand
- AK Scientific
- Alichem
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Chemenu
- Crysdot
- Usbiological
Package
- 10mM(in 1mL DMSO)
- 1mg
- 5mg
- 10mg
- 25mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number6520CX
- Product descriptionS-(2-(6-(4-(3-(Dimethylamino)propoxy)phenylsulfonamido)pyridin-3-yl)-2-oxoethyl)ethanethioate
- Packaging1mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number6520CX
- Product descriptionS-(2-(6-(4-(3-(Dimethylamino)propoxy)phenylsulfonamido)pyridin-3-yl)-2-oxoethyl)ethanethioate
- Packaging5mg
- Price$226
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number6520CX
- Product descriptionS-(2-(6-(4-(3-(Dimethylamino)propoxy)phenylsulfonamido)pyridin-3-yl)-2-oxoethyl)ethanethioate
- Packaging10mg
- Price$286
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number940943373
- Product descriptionS-(2-(6-(4-(3-(Dimethylamino)propoxy)phenylsulfonamido)pyridin-3-yl)-2-oxoethyl)ethanethioate
- Packaging100mg
- Price$242.55
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number940943373
- Product descriptionS-(2-(6-(4-(3-(Dimethylamino)propoxy)phenylsulfonamido)pyridin-3-yl)-2-oxoethyl)ethanethioate
- Packaging1g
- Price$1029
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA117481
- Product descriptionS-(2-(6-(4-(3-(Dimethylamino)propoxy)phenylsulfonamido)pyridin-3-yl)-2-oxoethyl)ethanethioate 95+%
- Packaging100mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA117481
- Product descriptionS-(2-(6-(4-(3-(Dimethylamino)propoxy)phenylsulfonamido)pyridin-3-yl)-2-oxoethyl)ethanethioate 95+%
- Packaging250mg
- Price$268
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA117481
- Product descriptionS-(2-(6-(4-(3-(Dimethylamino)propoxy)phenylsulfonamido)pyridin-3-yl)-2-oxoethyl)ethanethioate 95+%
- Packaging1g
- Price$876
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0010340
- Product descriptionS-[2-[6-[[[4-[3-(DIMETHYLAMINO)PROPOXY]PHENYL]SULFONYL]AMINO]-3-PYRIDINYL]-2-OXOETHYL]ETHANETHIOC ACID ESTER 95.00%
- Packaging10MG
- Price$782.23
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4493
- Product descriptionKD5170
- Packaging10mM(in 1mL DMSO)
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4493
- Product descriptionKD5170
- Packaging10mg
- Price$182
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13214
- Product descriptionKD 5170 ≥98%
- Packaging1mg
- Price$34
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13214
- Product descriptionKD 5170 ≥98%
- Packaging5mg
- Price$128
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13214
- Product descriptionKD 5170 ≥98%
- Packaging10mg
- Price$202
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13214
- Product descriptionKD 5170 ≥98%
- Packaging25mg
- Price$465
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM174522
- Product descriptionS-(2-(6-(4-(3-(Dimethylamino)propoxy)phenylsulfonamido)pyridin-3-yl)-2-oxoethyl)ethanethioate 95%
- Packaging1g
- Price$916
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 6520CX | S-(2-(6-(4-(3-(Dimethylamino)propoxy)phenylsulfonamido)pyridin-3-yl)-2-oxoethyl)ethanethioate | 1mg | $133 | 2021-12-16 | Buy |
AK Scientific | 6520CX | S-(2-(6-(4-(3-(Dimethylamino)propoxy)phenylsulfonamido)pyridin-3-yl)-2-oxoethyl)ethanethioate | 5mg | $226 | 2021-12-16 | Buy |
AK Scientific | 6520CX | S-(2-(6-(4-(3-(Dimethylamino)propoxy)phenylsulfonamido)pyridin-3-yl)-2-oxoethyl)ethanethioate | 10mg | $286 | 2021-12-16 | Buy |
Alichem | 940943373 | S-(2-(6-(4-(3-(Dimethylamino)propoxy)phenylsulfonamido)pyridin-3-yl)-2-oxoethyl)ethanethioate | 100mg | $242.55 | 2021-12-16 | Buy |
Alichem | 940943373 | S-(2-(6-(4-(3-(Dimethylamino)propoxy)phenylsulfonamido)pyridin-3-yl)-2-oxoethyl)ethanethioate | 1g | $1029 | 2021-12-16 | Buy |
Ambeed | A117481 | S-(2-(6-(4-(3-(Dimethylamino)propoxy)phenylsulfonamido)pyridin-3-yl)-2-oxoethyl)ethanethioate 95+% | 100mg | $135 | 2021-12-16 | Buy |
Ambeed | A117481 | S-(2-(6-(4-(3-(Dimethylamino)propoxy)phenylsulfonamido)pyridin-3-yl)-2-oxoethyl)ethanethioate 95+% | 250mg | $268 | 2021-12-16 | Buy |
Ambeed | A117481 | S-(2-(6-(4-(3-(Dimethylamino)propoxy)phenylsulfonamido)pyridin-3-yl)-2-oxoethyl)ethanethioate 95+% | 1g | $876 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0010340 | S-[2-[6-[[[4-[3-(DIMETHYLAMINO)PROPOXY]PHENYL]SULFONYL]AMINO]-3-PYRIDINYL]-2-OXOETHYL]ETHANETHIOC ACID ESTER 95.00% | 10MG | $782.23 | 2021-12-16 | Buy |
ApexBio Technology | A4493 | KD5170 | 10mM(in 1mL DMSO) | $170 | 2021-12-16 | Buy |
ApexBio Technology | A4493 | KD5170 | 10mg | $182 | 2021-12-16 | Buy |
Cayman Chemical | 13214 | KD 5170 ≥98% | 1mg | $34 | 2024-03-01 | Buy |
Cayman Chemical | 13214 | KD 5170 ≥98% | 5mg | $128 | 2024-03-01 | Buy |
Cayman Chemical | 13214 | KD 5170 ≥98% | 10mg | $202 | 2024-03-01 | Buy |
Cayman Chemical | 13214 | KD 5170 ≥98% | 25mg | $465 | 2024-03-01 | Buy |
Chemenu | CM174522 | S-(2-(6-(4-(3-(Dimethylamino)propoxy)phenylsulfonamido)pyridin-3-yl)-2-oxoethyl)ethanethioate 95% | 1g | $916 | 2021-12-16 | Buy |
Properties
Boiling point :637.9±65.0 °C(Predicted)
Density :1.310±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :≥21.2 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH
form :solid
pka :9.29±0.28(Predicted)
color :White to yellow
Density :1.310±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :≥21.2 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH
form :solid
pka :9.29±0.28(Predicted)
color :White to yellow
Safety Information
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Description
KD 5170 is a mercaptoketone-based inhibitor of class I and II histone deacetylases (HDACs; IC50s = 20, 2,060, 75, 26, 950, 14, 85, 2,500, 150, and 18 nM for HDAC1-10, respectively). It exhibits broad spectrum antitumor activity in vitro and in vivo. KD 5170 increases the acetylation of histones and activates caspases 3, 8, and 9, leading to apoptosis in primary myeloma cells.Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
Nanjing Doge Biomedical Technology Co., Ltd
LEAPCHEM CO., LTD.
Sichuan Biosynce Pharmatech Co., Ltd.
Aladdin Scientific
Amadis Chemical Company Limited
Chengdu HappySyn Pharmaceutical Technology Co., Ltd.
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.