CP-547632
|
- $57 - $6683
- Product name: CP-547632
- CAS: 252003-65-9
- MF: C20H24BrF2N5O3S
- MW: 532.4
- EINECS:200-258-5
- MDL Number:MFCD07772279
- Synonyms:CP-547632;3-(4-Bromo-2,6-difluorobenzyloxy)-5-(3-(4-pyrrolidin-1-ylbutyl)ureido)isothiazole-4-carboxylic acid amide;4-Isothiazolecarboxamide, 3-((4-bromo-2,6-difluorophenyl)methoxy)-5-((((4-(1-pyrrolidinyl)butyl)amino)carbonyl)amino)-;CP-547632(CP 547632);3-[(4-broMo-2,6-difluorophenyl)Methoxy]-5-[[[[4-(1-pyrrolidinyl)butyl]aMino]carbonyl]aMino]-4-isothiazolecarboxaMide;3-((4-Bromo-2,6-difluorobenzyl)oxy)-5-(3-(4-(pyrrolidin-1-yl)butyl)ureido)isothiazole-4-carboxami;3-((4-Bromo-2,6-difluorobenzyl)oxy)-5-(3-(4-(pyrrolidin-1-yl)butyl)ureido)isothiazole-4-carbox;3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide
24 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
Package
- 500μg
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500MG
- 1g
- ManufacturerAK Scientific
- Product numberX5494
- Product description3-(4-Bromo-2,6-difluorobenzyloxy)-5-(3-(4-pyrrolidin-1-ylbutyl)ureido)isothiazole-4-carboxylicacidamide
- Packaging250mg
- Price$6683
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA867793
- Product descriptionCp-547632 95%
- Packaging5mg
- Price$105
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA867793
- Product descriptionCp-547632 95%
- Packaging10mg
- Price$137
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA867793
- Product descriptionCp-547632 95%
- Packaging25mg
- Price$179
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA867793
- Product descriptionCp-547632 95%
- Packaging50mg
- Price$284
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005167
- Product descriptionCP-547632 95.00%
- Packaging500MG
- Price$4966.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB102944
- Product description3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide
- Packaging25mg
- Price$750
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB102944
- Product description3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide
- Packaging10mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB102944
- Product description3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide
- Packaging5mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB102944
- Product description3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide
- Packaging2mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB102944
- Product description3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide
- Packaging1mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21773
- Product descriptionCP 547,632 ≥98%
- Packaging5mg
- Price$437
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21773
- Product descriptionCP 547,632 ≥98%
- Packaging1mg
- Price$107
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21773
- Product descriptionCP 547,632 ≥98%
- Packaging500μg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM280772
- Product descriptionCP-547632 98%
- Packaging100mg
- Price$1312
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0003189
- Product descriptionCP-547632 >99.0%
- Packaging100mg
- Price$950
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | X5494 | 3-(4-Bromo-2,6-difluorobenzyloxy)-5-(3-(4-pyrrolidin-1-ylbutyl)ureido)isothiazole-4-carboxylicacidamide | 250mg | $6683 | 2021-12-16 | Buy |
| Ambeed | A867793 | Cp-547632 95% | 5mg | $105 | 2021-12-16 | Buy |
| Ambeed | A867793 | Cp-547632 95% | 10mg | $137 | 2021-12-16 | Buy |
| Ambeed | A867793 | Cp-547632 95% | 25mg | $179 | 2021-12-16 | Buy |
| Ambeed | A867793 | Cp-547632 95% | 50mg | $284 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0005167 | CP-547632 95.00% | 500MG | $4966.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB102944 | 3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide | 25mg | $750 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB102944 | 3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide | 10mg | $400 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB102944 | 3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide | 5mg | $220 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB102944 | 3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide | 2mg | $100 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB102944 | 3-[(4-Bromo-2,6-difluorobenzyl)oxy]-5-[3-[4-(pyrrolidin-1-yl)butyl]ureido]isothiazole-4-carboxamide | 1mg | $60 | 2021-12-16 | Buy |
| Cayman Chemical | 21773 | CP 547,632 ≥98% | 5mg | $437 | 2024-03-01 | Buy |
| Cayman Chemical | 21773 | CP 547,632 ≥98% | 1mg | $107 | 2024-03-01 | Buy |
| Cayman Chemical | 21773 | CP 547,632 ≥98% | 500μg | $57 | 2024-03-01 | Buy |
| Chemenu | CM280772 | CP-547632 98% | 100mg | $1312 | 2021-12-16 | Buy |
| ChemScene | CS-0003189 | CP-547632 >99.0% | 100mg | $950 | 2021-12-16 | Buy |
Properties
Boiling point :548.6±50.0 °C(Predicted)
Density :1.532
storage temp. :2-8°C
solubility :DMSO: 94 mM
form :A solid
pka :12.50±0.70(Predicted)
color :White to light yellow
Density :1.532
storage temp. :2-8°C
solubility :DMSO: 94 mM
form :A solid
pka :12.50±0.70(Predicted)
color :White to light yellow
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
CP 547,632 is an orally bioavailable and potent inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and basic fibroblast growth factor (bFGF) with IC50 values of 11 and 9 nM, respectively, in an enzyme assay. It is selective for VEGFR2 and bFGF over EGFR, PDGF receptor β (PDGFRβ), and related tyrosine kinases. CP 547,632 inhibits VEGFR2 autophosphorylation induced by VEGF in porcine aortic endothelial cells transfected with VEGFR2 (IC50 = 6 nM) and in a xenograft mouse model using NIH3T3/H-Ras cells (EC50 = 590 nM). It decreases angiogenesis induced by VEGF or bFGF and suppresses tumor growth in athymic mice.More related product prices
PENTAFLUOROBENZYL BROMIDERelated product price
- PENTAFLUOROBENZYL BROMIDE
$10-2506.47
Suppliers and manufacturers
CONIER CHEM AND PHARMA LIMITED
InvivoChem
Shanghai Likang New Materials Co., Limited
Amadis Chemical Company Limited
Hangzhou FuRun Pharmaceutical Technology Co., Ltd
Shanghai Boyle Chemical Co., Ltd.
Chembest Research Laboratories Limited
