Pemetrexed Disodium Heptahydrate
19 prices
-
Ambeed
-
American Custom Chemicals Corporation
-
Cayman Chemical
-
Medical Isotopes, Inc.
-
Sigma-Aldrich
-
TRC
- 5MG
- 10MG
- 50mg
- 100MG
- 250mg
- y0001538
- y0001539
- 500mg
- 1g
- 5g
- 25g
Manufacturer |
Product number |
Product description |
Packaging |
Price |
Updated |
Buy |
Ambeed
| A209789 |
Sodium(S)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioateheptahydrate 98+% |
1g |
$23 |
2021-12-16 |
Buy |
Ambeed
| A209789 |
Sodium(S)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioateheptahydrate 98+% |
5g |
$93 |
2021-12-16 |
Buy |
Ambeed
| A209789 |
Sodium(S)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioateheptahydrate 98+% |
25g |
$372 |
2021-12-16 |
Buy |
American Custom Chemicals Corporation
| API0024628 |
PEMETREXED DISODIUM HEPTAHYDRATE 95.00% |
5MG |
$171.6 |
2021-12-16 |
Buy |
American Custom Chemicals Corporation
| API0024628 |
PEMETREXED DISODIUM HEPTAHYDRATE 95.00% |
10MG |
$721.88 |
2021-12-16 |
Buy |
American Custom Chemicals Corporation
| API0024628 |
PEMETREXED DISODIUM HEPTAHYDRATE 95.00% |
100MG |
$1732.5 |
2021-12-16 |
Buy |
Cayman Chemical
| 14269 |
Pemetrexed (sodium salt hydrate) ≥98% |
5mg |
$61 |
2024-03-01 |
Buy |
Cayman Chemical
| 14269 |
Pemetrexed (sodium salt hydrate) ≥98% |
10mg |
$112 |
2024-03-01 |
Buy |
Cayman Chemical
| 14269 |
Pemetrexed (sodium salt hydrate) ≥98% |
50mg |
$468 |
2024-03-01 |
Buy |
Cayman Chemical
| 14269 |
Pemetrexed (sodium salt hydrate) ≥98% |
100mg |
$816 |
2024-03-01 |
Buy |
Medical Isotopes, Inc.
| 66649 |
Pemetrexed disodium heptahydrate |
10mg |
$610 |
2021-12-16 |
Buy |
Medical Isotopes, Inc.
| 66649 |
Pemetrexed disodium heptahydrate |
250mg |
$1475 |
2021-12-16 |
Buy |
Sigma-Aldrich
| 1500659 |
Pemetrexed for system suitability United States Pharmacopeia (USP) Reference Standard |
100mg |
$436 |
2024-03-01 |
Buy |
Sigma-Aldrich
| SML1490 |
Pemetrexed for system suitability ≥98% (HPLC) |
50mg |
$435 |
2024-03-01 |
Buy |
Sigma-Aldrich
| Y0001538 |
Pemetrexed for system suitability European Pharmacopoeia (EP) Reference Standard |
y0001538 |
$153 |
2024-03-01 |
Buy |
Sigma-Aldrich
| Y0001539 |
Pemetrexed disodium heptahydrate European Pharmacopoeia (EP) Reference Standard |
y0001539 |
$153 |
2024-03-01 |
Buy |
Properties
storage temp. :2-8°C
solubility :H2O: soluble30mg/mL, clear
form :powder
color :white to beige
Water Solubility :H2O: 30mg/mL, clear
Stability :Stable for 1 year as supplied. Solutions in distilled water may be stored at -20° for up to 31month.
InChIKey :AEZRDYKQLPDYEH-YTCXBBKHNA-N
SMILES :C(C1=CNC2NC(N)=NC(=O)C1=2)CC1C=CC(C(=O)N[C@H](C(=O)O)CCC(=O)O)=CC=1.[NaH].O |&1:20,r|
Safety Information
Symbol(GHS): |

|
Signal word: |
Danger |
Hazard statements: |
Code |
Hazard statements |
Hazard class |
Category |
Signal word |
Pictogram |
P-Codes |
H315 |
Causes skin irritation |
Skin corrosion/irritation |
Category 2 |
Warning |
 |
P264, P280, P302+P352, P321,P332+P313, P362 |
H319 |
Causes serious eye irritation |
Serious eye damage/eye irritation |
Category 2A |
Warning |
 |
P264, P280, P305+P351+P338,P337+P313P |
H341 |
Suspected of causing genetic defects |
Germ cell mutagenicity |
Category 2 |
Warning |
|
P201,P202, P281, P308+P313, P405,P501 |
H372 |
Causes damage to organs through prolonged or repeated exposure |
Specific target organ toxicity, repeated exposure |
Category 1 |
Danger |
 |
P260, P264, P270, P314, P501 |
|
Precautionary statements: |
P202 |
Do not handle until all safety precautions have been read and understood. |
P260 |
Do not breathe dust/fume/gas/mist/vapours/spray. |
P264 |
Wash hands thoroughly after handling. |
P264 |
Wash skin thouroughly after handling. |
P302+P352 |
IF ON SKIN: wash with plenty of soap and water. |
P305+P351+P338 |
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
P308+P313 |
IF exposed or concerned: Get medical advice/attention. |
|
Description
Pemetrexed is pyrrotopyrimidine-based, multi-targeted antifolate with broad in vivo antitumor activity. Originally identified as a highly efficient substrate for folylpolyglutamate synthase, pemetrexed potently inhibits multiple folate-dependent enzymes involved in both purine and pyrimidine synthesis including thymidylate synthase (Ki = 109 nM), dihydrofolate reductase (Ki = 7 nM), glycinamide ribonucleotide formyltransferase (Ki = 9.3 μM), and aminoimidazole carboxamide ribonucleotide formyltransferase (Ki = 3.6 μM). Its antiproliferative activity has been demonstrated in a wide variety of solid tumors, including non-small cell lung, breast, mesothelioma, colorectal, pancreatic, gastric, bladder, cervix, and head and neck.
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