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ChemicalBook >> CAS DataBase List >> DAPIVIRINE,4-[[4-(2,4,6-TRIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL]AMINO]BENZONITRILE

DAPIVIRINE,4-[[4-(2,4,6-TRIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL]AMINO]BENZONITRILE

DAPIVIRINE,4-[[4-(2,4,6-TRIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL]AMINO]BENZONITRILE price.
  • $44 - $2840
  • Product name: DAPIVIRINE,4-[[4-(2,4,6-TRIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL]AMINO]BENZONITRILE
  • CAS: 244767-67-7
  • MF: C20H19N5
  • MW: 329.4
  • EINECS:
  • MDL Number:MFCD09833899
  • Synonyms:DAPIVIRINE,4-[[4-(2,4,6-TRIMETHYLPHENYL)AMINO]PYRIMIDIN-2-YL]AMINO]BENZONITRILE;Dapivirine;Dapivirine TMC120, AIDS-105293;4-[[4-[(2,4,6-TriMethylphenyl)aMino]-2-pyriMidinyl]aMino]benzonitrile;R 147681;TMC 120R147681;Benzonitrile, 4-[[4-[(2,4,6-triMethylphenyl)aMino]-2-pyriMidinyl]aMino]-;Dapivirine,TMC-120
40 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • TRC
  • Usbiological
Package
  • 10mM(in 1mL DMSO)
  • 1mg
  • 5mg
  • 10mg
  • 25MG
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1G
  • 1000mg
  • 10G
  • ManufacturerAK Scientific
  • Product numberY0218
  • Product descriptionDapivirine
  • Packaging1mg
  • Price$82
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA175194
  • Product descriptionDapivirine 98+%
  • Packaging5mg
  • Price$321
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA175194
  • Product descriptionDapivirine 98+%
  • Packaging10mg
  • Price$481
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA175194
  • Product descriptionDapivirine 98+%
  • Packaging50mg
  • Price$1063
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA175194
  • Product descriptionDapivirine 98+%
  • Packaging250mg
  • Price$1796
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008108
  • Product descriptionDAPIVIRINE 95.00%
  • Packaging25MG
  • Price$416.3
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008108
  • Product descriptionDAPIVIRINE 95.00%
  • Packaging1G
  • Price$807
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008108
  • Product descriptionDAPIVIRINE 95.00%
  • Packaging10G
  • Price$2840
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8554
  • Product descriptionDapivirine(TMC120)
  • Packaging5mg
  • Price$103
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8554
  • Product descriptionDapivirine(TMC120)
  • Packaging10mM(in 1mL DMSO)
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8554
  • Product descriptionDapivirine(TMC120)
  • Packaging25mg
  • Price$329
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS018831
  • Product descriptionDapivirine
  • Packaging250mg
  • Price$1778
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1534
  • Product descriptionDapivirine-R147681|TMC120 99%
  • Packaging5mg
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181229
  • Product descriptionDapivirine >98%
  • Packaging1000mg
  • Price$1208.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD20796
  • Product descriptionDapivirine
  • Packaging25mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD20796
  • Product descriptionDapivirine
  • Packaging50mg
  • Price$150
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y0218 Dapivirine 1mg $82 2021-12-16 Buy
Ambeed A175194 Dapivirine 98+% 5mg $321 2021-12-16 Buy
Ambeed A175194 Dapivirine 98+% 10mg $481 2021-12-16 Buy
Ambeed A175194 Dapivirine 98+% 50mg $1063 2021-12-16 Buy
Ambeed A175194 Dapivirine 98+% 250mg $1796 2021-12-16 Buy
American Custom Chemicals Corporation API0008108 DAPIVIRINE 95.00% 25MG $416.3 2021-12-16 Buy
American Custom Chemicals Corporation API0008108 DAPIVIRINE 95.00% 1G $807 2021-12-16 Buy
American Custom Chemicals Corporation API0008108 DAPIVIRINE 95.00% 10G $2840 2021-12-16 Buy
ApexBio Technology A8554 Dapivirine(TMC120) 5mg $103 2021-12-16 Buy
ApexBio Technology A8554 Dapivirine(TMC120) 10mM(in 1mL DMSO) $110 2021-12-16 Buy
ApexBio Technology A8554 Dapivirine(TMC120) 25mg $329 2021-12-16 Buy
Arctom AS018831 Dapivirine 250mg $1778 2021-12-16 Buy
Axon Medchem Axon1534 Dapivirine-R147681|TMC120 99% 5mg $88 2021-12-16 Buy
Biorbyt Ltd orb181229 Dapivirine >98% 1000mg $1208.7 2021-12-16 Buy
Biosynth Carbosynth FD20796 Dapivirine 25mg $100 2021-12-16 Buy
Biosynth Carbosynth FD20796 Dapivirine 50mg $150 2021-12-16 Buy

Properties

Melting point :218-222°C
Boiling point :557.9±60.0 °C(Predicted)
Density :1.23±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :DMSO (Slightly), Methanol (Slightly)
pka :4.74±0.10(Predicted)
form :Solid
color :Off-White to Light Beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are highly specific and potent allosteric inhibitors of HIV-1 reverse transcriptase. Dapivirine, a diarylpyrimidine derivative of the potent NNRTI efavirenz , inhibits HIV-1 reverse transcriptase with an IC50 value of 24 nM in vitro. It impedes the late stages of HIV-1 infection by interfering with HIV-1 Gag-Pol polyprotein processing.

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