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ChemicalBook--->CAS DataBase List--->3004676-87-0

3004676-87-0

3004676-87-0 Structure

3004676-87-0 Structure
IdentificationBack Directory
[Name]

FXR/CES2 modulator 1
[CAS]

3004676-87-0
[Synonyms]

FXR/CES2 modulator 1
Hazard InformationBack Directory
[Uses]

FXR/CES2 modulator 1 (compound LE-77) is a doul modulator that activates FXR and inhibits CES2. FXR/CES2 modulator 1 effectively mitigates the intestinal toxicity of irinotecan[1].
[References]

[1] Zhijun Cao, et al. Discovery of the FXR/CES2 dual modulator LE-77 for the treatment of irinotecan-induced delayed diarrhea. Bioorg Chem. 2024 Sep 29:153:107852. DOI:10.1016/j.bioorg.2024.107852
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Company Name: Shanghai Beckham Medical Technology Co., Ltd  
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