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ChemicalBook--->CAS DataBase List--->50539-45-2

50539-45-2

50539-45-2 Structure

50539-45-2 Structure
IdentificationBack Directory
[Name]

N-(1-ANILINONAPHTHYL-4)-MALEIMIDE
[CAS]

50539-45-2
[Synonyms]

ANM
N-(1-Anilinophenyl)maleimide
N-(1-ANILINONAPHTHYL-4)-MALEIMIDE
N-(4-ANILINO-1-NAPHTHYL)MALEIMIDE
N-(1-anilinonaphthalyl)-4-maleimide
N-(1-ANILINONAPHTHYL-4)-MALEIMIDE[ANM]
N-[4-(Phenylamino)-1-naphtyl]maleimide
N-MaleiMido-N`-phenyl-1,4-NaphthalenediaMine
1-(4-Anilino-1-naphtyl)-3-pyrroline-2,5-dione
1-[4-(phenylamino)naphthyl]-1H-pyrrole-2,5-dione
N-(4-ANILINO-1-NAPHTHYL)MALEIMIDE, FOR F LUORESCENCE
1-(4-(PHENYLAMINO)-1-NAPHTHALENYL)-1H-PYRROLE-2,5-DIONE
1-[4-(phenylamino)naphthalen-1-yl]-2,5-dihydro-1H-pyrrole-2,5-dione
[EINECS(EC#)]

256-618-8
[Molecular Formula]

C20H14N2O2
[MDL Number]

MFCD00042694
[MOL File]

50539-45-2.mol
[Molecular Weight]

314.34
Chemical PropertiesBack Directory
[Appearance]

red powder
[Melting point ]

207 °C
[Boiling point ]

454.02°C (rough estimate)
[density ]

1.2303 (rough estimate)
[refractive index ]

1.5700 (estimate)
[pka]

3.50±0.30(Predicted)
[CAS DataBase Reference]

50539-45-2
Hazard InformationBack Directory
[Chemical Properties]

red powder
[Uses]

N-(4-Anilino-1-naphthyl)maleimide is a fluorescent probe that can be used to detect thiol groups in proteins. N-(4-Anilino-1-naphthyl)maleimide reacts with thiol groups and immediately produces a stable fluorescent compound with the λex=355 nm, λem=448 nm[1].
[References]

[1] T Honda, et al. Characterization of the reactivity of sulphydryl groups in tryptophanase by a dual-monitoring high-performance liquid chromatographic system with a site-directed fluorescent reagent. J Chromatogr. 1986 Dec 26;371:353-60. DOI:10.1016/s0021-9673(01)94718-1
[2] S Chaen, et al. Fluorescence properties and contraction characteristics of ANM (N-(1-anilinonaphthyl-4)maleimide)-labeled rabbit psoas muscle fibers. J Biochem. 1985 Oct;98(4):939-47. DOI:10.1093/oxfordjournals.jbchem.a135374
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

3
[F ]

8-10-21
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