p-Ethynylphenylalanine hydrochloride NEW
| Price | $30 | $45 | $64 |
| Package | 10mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-27 |
Product Details
| Product Name: p-Ethynylphenylalanine hydrochloride | CAS No.: 188640-63-3 |
| Purity: 99.03% | Supply Ability: 10g |
| Release date: 2025/04/27 |
Product Introduction
Bioactivity
| Name | p-Ethynylphenylalanine hydrochloride |
| Description | p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent, and specific inhibitor of TPH[1]. Its potential to selectively and reversibly inhibit serotonin biosynthesis may contribute to characterizing the role of serotonin in behavioral and physiological activities[1]. |
| In vitro | p-Ethynylphenylalanine hydrochloride was demonstrated to inhibit competitively and reversibly TPH in vitro (Ki = 32.6 +/- 6.2 microM vs. tryptophan)[1]. |
| In vivo | Administration of p-Ethynylphenylalanine hydrochloride (30 mg/kg) to rats produced a 95 +/- 5% decrease in TPH activity in brain homogenates and a concomitant decrease in serotonin and 5-hydroxyindole-3-acetic acid levels (85%) at 24 h after injection[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : 12 mg/mL (53.17 mM), Sonication is recommended. DMSO : 99 mg/mL (438.69 mM), Sonication is recommended. |
| Keywords | Tryptophan Hydroxylase | Tryptophan hydroxylase | tryptophan | TPH | serotonin | p-Ethynylphenylalanine Hydrochloride | pEthynylphenylalanine hydrochloride | p-Ethynylphenylalanine | p Ethynylphenylalanine hydrochloride | Inhibitor | inhibit | hydroxylase | 5-HT | 5-HIAA |
| Inhibitors Related | p-Ethynylphenylalanine | Mildronate | Tetrahydropapaverine hydrochloride | Casein | p-Fluoro-L-phenylalanine | Telotristat Etiprate | Ketoconazole | Bupicomide | Ro 61-8048 | Diethyl-pythiDC | Fenclonine | Nepicastat hydrochloride |
| Related Compound Libraries | Bioactive Compound Library | Inhibitor Library | NO PAINS Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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