(1S)-2,2,2-TRIFLUORO-1-NAPHTHYLETHYLAMINE synthesis

1synthesis methods

Product Name:(1S)-2,2,2-TRIFLUORO-1-NAPHTHYLETHYLAMINE
CAS Number:1213116-97-2
Molecular formula:C12H10F3N
Molecular Weight:225.21

7519-87-1
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(1S)-2,2,2-TRIFLUORO-1-NAPHTHYLETHYLAMINE

1213116-97-2
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$221.00/100mg

Yield:-

Steps:

Multi-step reaction with 2 steps
1: [(pyridinooxazoline)PdCl₂]; silver tetrafluoroborate / 1,2-dichloro-ethane / 20 h / 65 °C / Molecular sieve
2: [(pyridinooxazoline)PdCl₂]; silver hexafluoroantimonate; periodic acid; sulfuric acid / acetonitrile; water

References:

Johnson, Thomas;Luo, Bo;Lautens, Mark [Journal of Organic Chemistry,2016,vol. 81,# 12,p. 4923 - 4930]

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(1S)-2,2,2-TRIFLUORO-1-NAPHTHYLETHYLAMINE synthesis