Identification | Back Directory | [Name]
GerMacrone 4,5-epoxide | [CAS]
92691-35-5 | [Synonyms]
(4S,5S)-(+)-Germacrone 4,5-epoxide (1S,6E,10S)-6,10-Dimethyl-3-(1-methylethylidene)-11-oxabicyclo[8.1.0]undec-6-en-4-one 11-Oxabicyclo[8.1.0]undec-6-en-4-one, 6,10-dimethyl-3-(1-methylethylidene)-, (1S,6E,10S)- | [Molecular Formula]
C15H22O2 | [MOL File]
92691-35-5.mol | [Molecular Weight]
234.33 |
Hazard Information | Back Directory | [Uses]
Germacrone 4,5-epoxide is a sesquiterpene that can be isolated from Curcuma cf. viridiflora. Germacrone 4,5-epoxide has excellent anti-leukemic activities[1]. | [Definition]
ChEBI: Germacrone 4,5-epoxide is a germacrane sesquiterpenoid. | [References]
[1] Anuchapreeda S, et al. Cytotoxicity and inhibition of leukemic cell proliferation by sesquiterpenes from rhizomes of Mah-Lueang (Curcuma cf. viridiflora Roxb.). Bioorg Med Chem Lett. 2018 Feb 1;28(3):410-414. DOI:10.1016/j.bmcl.2017.12.029 |
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