Anti-PNK antibody ,Mouse monoclonal 化學特性,用途語,生産方法
使用
Monoclonal Anti-PNK antibody produced in mouse has been used in immunoblotting and immunoprecipitation.
一般的な説明
Monoclonal Anti-PNK (mouse IgG1 isotype) is derived from the hybridoma H101.5 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a human polynucleotide kinase 3′-phosphatase (PNK) recombinant protein. PNK comprises of a central phosphatase domain that is flanked by an N-terminal forkhead-associated (FHA) domain and a C-terminal kinase domain on either sides.
Biochem/physiol Actions
PNK is a mammalian DNA repair enzyme which catalyzes the phosphorylation of DNA 5′-hydroxyl termini and the dephosphorylation of 3′-phosphate termini. PNK is involved in the single-strand break repair pathway and the non-homologous end joining pathway for double strand break repair. Mutations in PNK result in neurological abnormalities.
Anti-PNK antibody ,Mouse monoclonal 上流と下流の製品情報
原材料
準備製品