ChemicalBook >> CAS DataBase List >>Aclerastide
Aclerastide
- CAS No.
- 227803-63-6
- Chemical Name:
- Aclerastide
- Synonyms
- DSC127;DSC-127;DSC 127;Aclerastide;NorLeu-3A(1-7);NorLeu-3-A(1-7);1-7-Angiotensin II, 3-L-norleucine-5-L-isoleucine-
- CBNumber:
- CB83166343
- Molecular Formula:
- C42H64N12O11
- Molecular Weight:
- 913.03136
- MDL Number:
- MOL File:
- 227803-63-6.mol
Last updated:2025-04-17 18:22:24
| Density | 1.45±0.1 g/cm3(Predicted) |
|---|---|
| pka | 3.29±0.20(Predicted) |
| form | Solid |
| color | White to off-white |
| FDA UNII | YYD6UT8T47 |
Aclerastide Chemical Properties,Uses,Production
Uses
Aclerastide is a peptide analog of angiotensin II, and a potential treatment for diabetic foot ulcers.
in vivo
Aclerastide (0.1 mg/wound; day for 5 days) shows superior efficacy in the db/db mouse model of wound healing[1].
Aclerastide (topically administered; 100 μL; once a day; for 14 days) elevates levels of reactive oxygen species and of active MMP-9[2].
| Animal Model: | db/db mice[2] |
| Dosage: | 100 μL |
| Administration: | Topically administered, once a day, for 14 days |
| Result: | Upregulated reactive oxygen species during inflammation. Increased the levels of the detrimental active MMP-9 in diabetic wounds. |
Aclerastide Preparation Products And Raw materials
Raw materials
Preparation Products
Aclerastide Suppliers
Global( 15)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32268 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19654 | 58 |
| Changsha MOL Changes Biotechnology Co., Ltd. | +8619375158599 | info@molchanges.com | China | 5221 | 58 |
| Creative Peptides | info@creative-peptides.com | United States | 6083 | 56 | |
| Chengdu Youngshe Chemical Co., Ltd. | +86-17380623303 +86-17380623303 | Caroline@youngshechem.com | China | 4804 | 58 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 | Eric@peptidego.com | China | 7061 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| Shaoxing Junyu Biotechnology Co., LTD | 0571-88211921 19105816207 | sales4@gotopbio.com | China | 5147 | 58 |
| Hangzhou Sinoda Pharmaceutical Technology Co. LTD | 0571-87213919 17306812703 | 3007955328@qq.com | China | 6628 | 58 |
| Shanghai HongTide Biotechnology Co.,Ltd. | 19961912513 | sales@hongtide.com | China | 4604 | 58 |
Aclerastide
DSC 127
DSC127
DSC-127
NorLeu-3-A(1-7)
NorLeu-3A(1-7)
1-7-Angiotensin II, 3-L-norleucine-5-L-isoleucine-
227803-63-6