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ChemicalBook >> CAS DataBase List >>Glecaprevir

Glecaprevir

CAS No.
1365970-03-1
Chemical Name:
Glecaprevir
Synonyms
ABT-493;CS-2616;Glecaprevir;A-1282576.0;Glecaprevir INN;Glecaprevir API;Glecaprevir 13CD3;ABT-493(Glecaprevir);Glecaprevir(ABT-493);Glecaprevir, 10 mM in DMSO
CBNumber:
CB83159912
Molecular Formula:
C38H46F4N6O9S
Molecular Weight:
838.87
MDL Number:
MFCD30533436
MOL File:
1365970-03-1.mol
Last updated:2025-05-07 12:58:23

Glecaprevir Properties

Melting point >186°C (dec.)
Density 1.46±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
pka 4.46±0.40(Predicted)
form Solid
color White to Off-White
FDA UNII K6BUU8J72P

SAFETY

Risk and Safety Statements

Glecaprevir price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 27934 Glecaprevir 1365970-03-1 1mg $44 2024-03-01 Buy
Cayman Chemical 27934 Glecaprevir 1365970-03-1 25mg $745 2024-03-01 Buy
Cayman Chemical 27934 Glecaprevir 1365970-03-1 5mg $193 2024-03-01 Buy
Cayman Chemical 27934 Glecaprevir 1365970-03-1 10mg $341 2024-03-01 Buy
ChemScene CS-8098 Glecaprevir 99.93% 1365970-03-1 5mg $420 2021-12-16 Buy
Product number Packaging Price Buy
27934 1mg $44 Buy
27934 25mg $745 Buy
27934 5mg $193 Buy
27934 10mg $341 Buy
CS-8098 5mg $420 Buy

Glecaprevir Chemical Properties,Uses,Production

Approval

On 19 December 2016, AbbVie submitted a new drug application to the U.S. Food and Drug Administration for the glecaprevir/pibrentasvir (trade name Mavyret) regimen for the treatment of all major genotypes of chronic hepatitis C. On 3 August 2017 the FDA approved the combination for hepatitis C treatment. In Europe, it was approved on 17 August 2017 for the same indication, under the trade name Maviret.

Uses

Glecaprevir is an antiviral drug used in the treatment of patients with hepatitis C virus (HCV) genotype 1-6, of special interest for the treatment of patients with chronic kidney disease also suffering from HCV.

Uses

Glecaprevir (INN) is a hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease inhibitor that was identified jointly by AbbVie and Enanta Pharmaceuticals. It is being developed as a treatment of chronic hepatitis C infection in co-formulation with an HCV NS5A inhibitor pibrentasvir. Together they demonstrated potent antiviral activity against major HCV genotypes and high barriers to resistance in vitro.

Side effects

The most common adverse effects, observed in at least 10% of phase 3 trial participants, were headache and fatigue.

Glecaprevir Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 107)Suppliers
Supplier Tel Email Country ProdList Advantage
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. 		+86-18600796368 +86-18600796368 sales@sjar-tech.com China 485 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
TianYuan Pharmaceutical CO.,LTD 		+86-755-23284190 13684996853 sales@tianpharm.com CHINA 304 58
Huaian yishu technology co.,ltd 		86-0517-85883738 13852390259 sales@yishuchem.com CHINA 53 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29807 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32268 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30230 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
Shanxi Xuanran Import and Export Trade Co., Ltd. 		+8617735180244 mike_yan@xuanranglobal.com CHINA 4017 58
AFINE CHEMICALS LIMITED 		+86-0571-85134551 sales@afinechem.com China 15229 58

Related articles

  • Glecaprevir-Pibrentasvir (Mavyret)
  • MAVYRET is a prescription medicine used to treat adults and children 12 years of age and older or weighing at least 99 pounds ....
  • Dec 21，2021

View Lastest Price from Glecaprevir manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Glecaprevir pictures 2025-05-07 Glecaprevir
1365970-03-1
 US $32.00-77.00 / mg 99.69% 10g TargetMol Chemicals Inc.
Glecaprevir pictures 2025-01-13 Glecaprevir
1365970-03-1
 US $0.00 / g 1g More Than 99% 50kg/Month BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Glecaprevir. pictures 2025-01-13 Glecaprevir.
1365970-03-1
 US $0.00 / g 1g More Than 99% 50kg/Month BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
  • Glecaprevir pictures
  • Glecaprevir
    1365970-03-1
  • US $32.00-77.00 / mg
  • 99.69%
  • TargetMol Chemicals Inc.
  • Glecaprevir pictures
  • Glecaprevir
    1365970-03-1
  • US $0.00 / g
  • More Than 99%
  • BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
  • Glecaprevir. pictures
  • Glecaprevir.
    1365970-03-1
  • US $0.00 / g
  • More Than 99%
  • BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.

Glecaprevir Spectrum

Glecaprevir (33R,35S,91R,92R,5S,E)-5-(tert-butyl)-N-((1R,2R)-2-(difluoromethyl)-1-(((1-methylcyclopropyl)sulfonyl)carbamoyl)cyclopropyl)-14,14-difluoro-4,7-dioxo-2,8,10-trioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopentanacyclotetradecaphan-12-ene-35 Glecaprevir API (1R,2R)-N-[[[(1R,2R)-2-[[4,4-Difluoro-4-(3-hydroxy-2-quinoxalinyl)-2-buten-1-yl]oxy]cyclopentyl]oxy]carbonyl]-3-methyl-L-valyl-(4R)-4-hydroxy-L-prolyl-1-amino-2-(difluoromethyl)-N-[(1-methylcyclopropyl)sulfonyl]cyclopropanecarboxamide cyclic (1→2)-ether ABT-493(Glecaprevir) CS-2616 ABT-493;ABT 493;ABT493;GLECAPREVIR Glecaprevir(ABT-493) Cyclopropanecarboxamide, N-[[[(1R,2R)-2-[[4,4-difluoro-4-(3-hydroxy-2-quinoxalinyl)-2-buten-1-yl]oxy]cyclopentyl]oxy]carbonyl]-3-methyl-L-valyl-(4R)-4-hydroxy-L-prolyl-1-amino-2-(difluoromethyl)-N-[(1-methylcyclopropyl)sulfonyl]-, cyclic (1→2)-ether, (1R,2R)- Glecaprevir INN Glecaprevir 13CD3 ABT-493 (33R,35S,91R,92R,5S,E)-5-(tert-Butyl)-N-((1R,2R)-2-(difluoromethyl)-1-(((1-methylcyclopropyl)sulfonyl)carbamoyl)cyclopropyl)-14,14-difluoro-4,7-dioxo-2,8,10-trioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopentanacyclotetradecaphan-12-ene-35-carboxamide Glecaprevir, 10 mM in DMSO A-1282576.0 1365970-03-1 1367970-03-1 C38H46F4N6O9S