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ChemicalBook >> CAS DataBase List >>BUTEIN

BUTEIN

CAS No.
487-52-5
Chemical Name:
BUTEIN
Synonyms
BUTANOL;2',3,4,4'-TETRAHYDROCHALCONE;(2E)-;BUTEIN;CS-5675;BUTEIN(P);CCG208298;BUTEIN(SH);Butein >AC 1NQY7L)
CBNumber:
CB8136455
Molecular Formula:
C15H12O5
Molecular Weight:
272.25
MDL Number:
MFCD00017300
MOL File:
487-52-5.mol
MSDS File:
SDS
Last updated:2025-01-27 09:38:02

BUTEIN Properties

Melting point 216°C
Boiling point 560.9±50.0 °C(Predicted)
Density 1.483±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: >50 mg/mL
form solid
pka 7.44±0.35(Predicted)
color yellow
LogP 2.405 (est)
CAS DataBase Reference 487-52-5(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 4WVS5M0LGF
UNSPSC Code 85151701
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Safety Statements  22-24/25
WGK Germany  3
HS Code  29145090

BUTEIN price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 72795 Butein analytical standard 487-52-5 10mg $259 2024-03-01 Buy
Sigma-Aldrich 203987 Butein - CAS 487-52-5 - Calbiochem A cell-permeable, reversible, substrate competitive, plant polyphenol that acts as a specific protein tyrosine kinase inhibitor. 487-52-5 5MG $272 2022-05-15 Buy
TCI Chemical B3803 Butein >98.0%(HPLC) 487-52-5 1g $304 2024-03-01 Buy
TCI Chemical B3803 Butein >98.0%(HPLC) 487-52-5 100mg $138 2024-03-01 Buy
Cayman Chemical 15371 Butein ≥95% 487-52-5 1mg $32 2024-03-01 Buy
Product number Packaging Price Buy
72795 10mg $259 Buy
203987 5MG $272 Buy
B3803 1g $304 Buy
B3803 100mg $138 Buy
15371 1mg $32 Buy

BUTEIN Chemical Properties,Uses,Production

Chemical Properties

Yellow Solid

Uses

Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-κB in activated human mast cells: suppression of tumor necrosis factor-α, interleukin (IL)-6, and IL-8. Anti-inflammatory agent

Definition

ChEBI: A chalcone that is (E)-chalcone bearing four additional hydroxy substituents at positions 2', 3, 4 and 4'.

General Description

Butein (2′,3,4,4′-tetrahydroxychalcone) is a chalcone and a flavonoid, that is produced in plants. It is a plant polyphenol and a bioactive constituent, that is extracted from the heartwood of?Dalbergia odorifera, Caragana jubata and?Rhus verniciflua?stokes, and the stem bark of cashews (Semecarpus anacardium).

Biochem/physiol Actions

Butein exhibit several pharmacological activities, such as anti-oxidant and anti-inflammatory activity. It stimulates apoptotic cell death of human cervical cancer cells. It has therapeutic potentials for chronic diseases, including liver tuberculosis, obesity, diabetes and hypertension. Butein can repress migration and invasion of bladder, breast and pancreatic cancer cells.

BUTEIN Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 240)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Chengdu GLP biotechnology Co Ltd 		028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd. 		+86-28-82633860; +8618080483897 sales@biopurify.com China 3772 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
Shanghai Standard Technology Co., Ltd. 		18502101150 ft-sales@nature-standard.com CHINA 1923 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29808 58
Wuhan ChemNorm Biotech Co.,Ltd. 		+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58
Hubei Ipure Biology Co., Ltd 		+8613367258412 ada@ipurechemical.com China 10244 58
Apeloa Pharmaceutical Co., Ltd. 		+86-0571-87635730 +8615858229168 chem1022@hengdian-group.com China 1478 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626 eric@witopchemical.com China 23541 58

View Lastest Price from BUTEIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Butein pictures 2025-04-02 Butein
487-52-5
 US $0.00 / MG 20MG 98%min 30kg/month WUHAN FORTUNA CHEMICAL CO., LTD
Butein pictures 2023-02-24 Butein
487-52-5
 US $0.00 / mg 20mg ≥98%(HPLC) 100 g Shanghai Standard Technology Co., Ltd.
Butein pictures 2020-01-10 Butein
487-52-5
 US $1.00 / KG 1KG ≥98% 20 tons Career Henan Chemical Co
  • Butein pictures
  • Butein
    487-52-5
  • US $0.00 / MG
  • 98%min
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • Butein pictures
  • Butein
    487-52-5
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.
  • Butein pictures
  • Butein
    487-52-5
  • US $1.00 / KG
  • ≥98%
  • Career Henan Chemical Co

BUTEIN Spectrum

(E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one 2',3,4,4'-Tetrahydroxychalcone BUTEIN(P) 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-, (2E)- Butein 2',3,4,4'-Tetrahydroxychalcone 2-[(E)-2-(2-aminophenyl)ethenyl]-5-methyl-quinolin-8-ol 2-[(E)-2-(2-aminophenyl)ethenyl]-5-methylquinolin-8-ol 2-[(E)-2-(2-aminophenyl)vinyl]-5-methyl-8-quinolinol 2-[(E)-2-(2-aminophenyl)vinyl]-5-methyl-quinolin-8-ol 2-[2-(2-aminophenyl)ethenyl]-5-methyl-quinolin-8-ol 2-[2-(2-aminophenyl)ethenyl]-5-methylquinolin-8-ol 2-[2-(2-aminophenyl)vinyl]-5-methyl-8-quinolinol 2-[2-(2-aminophenyl)vinyl]-5-methyl-quinolin-8-ol 2-[2-(2-aminophenyl)vinyl]-5-methylquinolin-8-ol BUTEIN 2',4',3,4-TETRAHYDROXYCHALCONE 2',3,4,4'-TETRAHYDROXYCHALCONE 3,4,2',4'-TETRAHYDROXYCHALCONE 1-(2,4-DIHYDROXYPHENYL)-3-(3,4-DIHYDROXYPHENYL)-2-PROPEN-1-ONE 1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propene-1-one (E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one 2',3,4,4'-Tetrahydroxy-trans-chalcone Einecs 207-659-5 BUTEIN(SH) BUTEIN WITH HPLC (2E)- Butein - CAS 487-52-5 - Calbiochem Butein > Butein Butein (E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one AC 1NQY7L) Butein (NSC-652892 CCG208298 CS-5675 2',3,4,4'-TETRAHYDROCHALCONE BUTANOL PDE4,Epidermal growth factor receptor,Inhibitor,EGFR,MAPK,ErbB-1,Apoptosis,Autophagy,FoxO3a,inhibit,cell,SIRT1,Phosphodiesterase (PDE),ERK,PKB,Butein,AKT,HeLa,HER1,p38,HepG2 (2E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one Butein, c-Met and EGFR tyrosine kinase inhibitor Butein-CAS 487-52-5 Butein, 10 mM in DMSO 487-52-5 Receptor Tyrosine Kinase Inhibitors Epidermal Growth Factor Receptor (EGFR) and Src BioChemical Cell Biology Cell Signaling and Neuroscience Kinase/Phosphatase Biology Aromatics Inhibitors Intermediates & Fine Chemicals Pharmaceuticals