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ChemicalBook >> CAS DataBase List >>Nemadectin

Nemadectin

CAS No.
102130-84-7
Chemical Name:
Nemadectin
Synonyms
AC-088;Nemadectin;LL-F-28249α;LL-F28249 alpha;S541A, LL-F28249 alpha;(6R,23S,25S)-5-O-Demethyl-28-deoxy-25-[(E)-1,3-dimethyl-1-butenyl]-6,28-epoxy-23-hydroxymilbemycin B;Milbemycin B,5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-buten-1-yl]-6,28-epoxy-23-hydroxy-,(6R,23S)-;(2R,2a'E,2a1'S,4S,4'E,5S,6S,6'R,8'E,11'R,15'S,17a'R,20'R,20a'R)-2a1',4,20'-Trihydroxy-5,6',8',19'-tetramethyl-6-((E)-4-methylpent-2-en-2-yl)-2a1',3,4,5,6,6',7',10',11',14',15',17a',20',20a'-tetradecahydro-2'H,17'H-spiro[pyran-2,13'-[11,15]methano[1,5]dioxacyclooctadecino[9,8,7-cd]benzofuran]-17'-one
CBNumber:
CB81179291
Molecular Formula:
C36H52O8
Molecular Weight:
612.79
MDL Number:
MFCD00866562
MOL File:
102130-84-7.mol
MSDS File:
SDS
Last updated:2025-04-17 18:22:24

Nemadectin Properties

alpha D26 +133° (c = 0.3 in acetone)
Boiling point 789.4±60.0 °C(Predicted)
Density 1.20±0.1 g/cm3(Predicted)
pka 12.46±0.70(Predicted)
form Solid
color White to off-white
FDA UNII 1Y8VJ1G3TY

SAFETY

Risk and Safety Statements

RIDADR  2588
HazardClass  6.1(b)
PackingGroup  III

Nemadectin price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 17454 Nemadectin ≥95% 102130-84-7 1mg $265 2021-12-16 Buy
Cayman Chemical 17454 Nemadectin ≥95% 102130-84-7 5mg $928 2021-12-16 Buy
Usbiological 285448 Nemadectin 102130-84-7 1mg $1214 2021-12-16 Buy
Usbiological N0980 Nemadectin 102130-84-7 1mg $561 2021-12-16 Buy
Biosynth Carbosynth FD32725 (6R,23S,25S)-5-O-Demethyl-28-Deoxy-25-((E)-1,3-Dimethyl-1-Butenyl)-6,28-Epoxy-23-Hydroxymilbemycin B 102130-84-7 2mg $700 2021-12-16 Buy
Product number Packaging Price Buy
17454 1mg $265 Buy
17454 5mg $928 Buy
285448 1mg $1214 Buy
N0980 1mg $561 Buy
FD32725 2mg $700 Buy

Nemadectin Chemical Properties,Uses,Production

Description

The nemadectins are fermentation products of Streptomyces cyaneogriseus noncyanogenus. Structurally, the nemadectins lack a disaccharide group at C-13 but differ from the milbemycins proper because they contain a trisubstituted double bond at C-26 in their side chains.

Uses

Nemadectin is the dominant member of a class of milbemycins bearing unsaturated longer chain groups at the 25-position. Nemadectin shows pronounced nematocidal and insecticidal activity. Nemadectin is the starting material for moxidectin, a commercial anthelmintic.

Uses

Nemadectin is a potent antiparasitic macrolide lactone.

in vivo

Nemadectin is highly effective at 0.6 mg/kg BW against natural infections of all major species of canine intestinal helminths, when administered as a single oral dose, either as a liquid or a tablet[1].

IC 50

Mite

Nemadectin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 71)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21629 55
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
AFINE CHEMICALS LIMITED 		+86-0571-85134551 sales@afinechem.com China 15350 58
Henan Aochuang Chemical Co.,Ltd. 		+86-0371-63689365 +8618638391208 sales@aochuangchem.com China 9297 58
Seasons Biotechnology Co., Ltd. 		+86-0576-89232655 +86-13566878689 info@seasonsbio.com China 47 58
SUZHOU SENFEIDA CHEMICAL CO.,LTD 		+86-0512-83500002 +8615195660023 sales@senfeida.com China 26362 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8467 58
Protheragen-ING 		+16313385890 info@protheragen-ing.com United States 3868 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
Huzhou fuhe Rui biological medicine co., ltd 13626726938 China 791 58

View Lastest Price from Nemadectin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Nemadectin pictures 2025-04-04 Nemadectin
102130-84-7
 US $0.00 / KG 25KG 97% 1tone Henan Aochuang Chemical Co.,Ltd.
  • Nemadectin pictures
  • Nemadectin
    102130-84-7
  • US $0.00 / KG
  • 97%
  • Henan Aochuang Chemical Co.,Ltd.
Nemadectin (6R,23S,25S)-5-O-Demethyl-28-deoxy-25-[(E)-1,3-dimethyl-1-butenyl]-6,28-epoxy-23-hydroxymilbemycin B AC-088 LL-F-28249α S541A, LL-F28249 alpha LL-F28249 alpha Milbemycin B,5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-buten-1-yl]-6,28-epoxy-23-hydroxy-,(6R,23S)- (2R,2a'E,2a1'S,4S,4'E,5S,6S,6'R,8'E,11'R,15'S,17a'R,20'R,20a'R)-2a1',4,20'-Trihydroxy-5,6',8',19'-tetramethyl-6-((E)-4-methylpent-2-en-2-yl)-2a1',3,4,5,6,6',7',10',11',14',15',17a',20',20a'-tetradecahydro-2'H,17'H-spiro[pyran-2,13'-[11,15]methano[1,5]dioxacyclooctadecino[9,8,7-cd]benzofuran]-17'-one 102130-84-7