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ChemicalBook >> CAS DataBase List >>SAHO

SAHO

CAS No.
29907-86-6
Chemical Name:
SAHO
Synonyms
SAHO;5′-[[(3S )-3-amino-3-carboxypropyl]sulfinyl]-5′-deoxy-adenosine;Adenosine, 5'-[[(3S)-3-amino-3-carboxypropyl]sulfinyl]-5'-deoxy-;(2S)-2-Amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methylsulfinyl]butanoic acid
CBNumber:
CB58570995
Molecular Formula:
C14H20N6O6S
Molecular Weight:
400.41
MDL Number:
MOL File:
29907-86-6.mol
Last updated:2025-04-17 18:22:24

SAHO Properties

Boiling point 893.1±75.0 °C(Predicted)
Density 2.04±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml
form A crystalline solid
pka 2.15±0.10(Predicted)
color White to off-white

SAHO Chemical Properties,Uses,Production

Uses

S-Adenosylhomocysteine sulfoxide is an inhibitor of catechol-O-methyltransferase (COMT) with an IC50 value of 860 μM. S-Adenosylhomocysteine sulfoxide can be used in the research of methylation reaction modulators[1].

Biological Activity

SAHO is a sulfoxide form of the methyl donor S-(5'-adenosyl)-L-methionine chloride and a substrate for radical SAM enzymes.1 It is reductively cleaved to S-adenosylhomocysteine , 5'-deoxyadenosine , and 5'-thioadenosine sulfenic acid by the radical SAM enzymes NosL or NosN.

References

1.Mandalapu, D., Ji, X., and Zhang, Q.Reductive cleavage of sulfoxide and sulfone by two radical S-adenosyl-L-methionine enzymesBiochemistry58(1)36-39(2019)

SAHO Preparation Products And Raw materials

Raw materials

Preparation Products

SAHO Suppliers

Global( 9)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32159 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9803 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 7165 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19727 58
Cayman Chemical Company 800-364-9897 sales@caymanchem.com China 21645 58
Biosynth Biological Technology (Suzhou) Co Ltd 51288865780 sales@biosynth.com China 233051 58

View Lastest Price from SAHO manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SAHO pictures 2024-10-24 SAHO
29907-86-6
US $423.00-93.00 / mg 10g TargetMol Chemicals Inc.
  • SAHO pictures
  • SAHO
    29907-86-6
  • US $423.00-93.00 / mg
  • TargetMol Chemicals Inc.
SAHO Adenosine, 5'-[[(3S)-3-amino-3-carboxypropyl]sulfinyl]-5'-deoxy- 5′-[[(3S )-3-amino-3-carboxypropyl]sulfinyl]-5′-deoxy-adenosine (2S)-2-Amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methylsulfinyl]butanoic acid 29907-86-6