ChemicalBook >> CAS DataBase List >>RO0335
RO0335
- CAS No.
- 867365-76-2
- Chemical Name:
- RO0335
- Synonyms
- RO0335;depulfavirine;RO-0335, 10 mM in DMSO;1,10-phenanthroline-6-carboxylicacid;5-methylsulfonylpyridine-4-carbonitrile;N-[4-(Aminosulfonyl)-2-chlorophenyl]-4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorobenzeneacetamide;Benzeneacetamide, N-[4-(aminosulfonyl)-2-chlorophenyl]-4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluoro-;Reverse Transcriptase,RO0335,RO 0335,nonnucleoside,novel,inhibit,diphenylether,potent,HIV-1,Ro-0335,Inhibitor
- CBNumber:
- CB42620013
- Molecular Formula:
- C21H13BrCl2FN3O4S
- Molecular Weight:
- 573.22
- MDL Number:
- MOL File:
- 867365-76-2.mol
- MSDS File:
- SDS
Last updated:2025-04-18 09:52:19
| storage temp. | Store at -20°C |
|---|---|
| solubility | DMSO : 250 mg/mL (436.13 mM; Need ultrasonic) |
| form | A solid |
| color | White to off-white |
| FDA UNII | ZP6H7RDZ5Q |
RO0335 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | API0014109 | RO-0335 95.00% | 867365-76-2 | 5MG | $503.4 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0014109 | RO-0335 95.00% | 867365-76-2 | 1G | $1855.35 | 2021-12-16 | Buy |
| Crysdot | CD12022255 | RO-0335 97% | 867365-76-2 | 250mg | $847 | 2021-12-16 | Buy |
RO0335 Chemical Properties,Uses,Production
Uses
RO-0335 is a novel and potent diphenylether nonnucleoside reverse transcriptase inhibitor(NNRTI). RO-0335 inhibits Wt HIV-1 with an IC50 of 1.1 nM and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates[1].
References
[1] Javanbakht H, et al. In vitro resistance development for RO-0335, a novel diphenylether nonnucleoside reverse transcriptase inhibitor. Antiviral Res. 2010;86(2):212-219. DOI:10.1016/j.antiviral.2010.02.323
RO0335 Preparation Products And Raw materials
Raw materials
Preparation Products
RO0335 Suppliers
Global( 37)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24727 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38665 | 58 | |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| China Kouting Group Limited | +86 (21) 5811-6473 5811-6475 | sales@koutingchina.com | China | 496 | 60 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7787 | 56 |
RO0335
N-[4-(Aminosulfonyl)-2-chlorophenyl]-4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorobenzeneacetamide
Benzeneacetamide, N-[4-(aminosulfonyl)-2-chlorophenyl]-4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluoro-
5-methylsulfonylpyridine-4-carbonitrile
1,10-phenanthroline-6-carboxylicacid
depulfavirine
Reverse Transcriptase,RO0335,RO 0335,nonnucleoside,novel,inhibit,diphenylether,potent,HIV-1,Ro-0335,Inhibitor
RO-0335, 10 mM in DMSO
867365-76-2
C21H13BrCl2FN3O4S