2,6-DIMETHYLPHENYL 2,4-DIMETHOXYPHENYL(2-(4-(4-METHYLPIPERAZIN-1-YL)PHENYLAMINO)PYRIMIDIN-4-YL)CARBAMATE性質(zhì)、用途與生產(chǎn)工藝

生物活性

WH-4-023 (KIN001-112, KIN112, Dual LCK/SRC inhibitor) 是一種有效的，口服具有活性的Lck/Src抑制劑，無(wú)細(xì)胞試驗(yàn)中IC50分別為2 nM 和 6 nM。對(duì)p38α和KDR的選擇性低300倍以上，還能有效抑制SIK（對(duì)SIK1、2、3的IC50分別為10、22、60 nM）。

靶點(diǎn)

Target	Value
Lck (Cell-free assay)	2 nM
Src (Cell-free assay)	6 nM

體外研究

WH-4-023對(duì)p38 和 KDR顯示出低活性。

2,6-DIMETHYLPHENYL 2,4-DIMETHOXYPHENYL(2-(4-(4-METHYLPIPERAZIN-1-YL)PHENYLAMINO)PYRIMIDIN-4-YL)CARBAMATE 上下游產(chǎn)品信息

上游原料

下游產(chǎn)品

2,6-DIMETHYLPHENYL 2,4-DIMETHOXYPHENYL(2-(4-(4-METHYLPIPERAZIN-1-YL)PHENYLAMINO)PYRIMIDIN-4-YL)CARBAMATE 試劑級(jí)價(jià)格

更新日期	產(chǎn)品編號(hào)	產(chǎn)品名稱(chēng)	CAS編號(hào)	包裝	價(jià)格
2025/02/08	HY-12299	WH-4-023	837422-57-8	1 mg	363元
2025/02/08	HY-12299	2,6-DIMETHYLPHENYL 2,4-DIMETHOXYPHENYL(2-(4-(4-METHYLPIPERAZIN-1-YL)PHENYLAMINO)PYRIMIDIN-4-YL)CARBAMATE WH-4-023	837422-57-8	5mg	800元

2,6-DIMETHYLPHENYL 2,4-DIMETHOXYPHENYL(2-(4-(4-METHYLPIPERAZIN-1-YL)PHENYLAMINO)PYRIMIDIN-4-YL)CARBAMATE 生產(chǎn)廠家

 

837422-57-8, 2,6-DIMETHYLPHENYL 2,4-DIMETHOXYPHENYL(2-(4-(4-METHYLPIPERAZIN-1-YL)PHENYLAMINO)PYRIMIDIN-4-YL)CARBAMATE 相關(guān)搜索:

• API
• Inhibitors
• 抑制劑
• 化工試劑
• 合成有機(jī)化合物配體
• 標(biāo)準(zhǔn)品
• 細(xì)胞生物學(xué)試劑
• 小分子抑制劑
• 小分子抑制劑，天然產(chǎn)物
• 化合物WH-4-023,10 MM DMSO 溶液
• WH-4-023,LCK和SRC抑制劑
• WH-4-023游離
• 化合物WH-4-023
• (2,4-二甲氧基苯基)(2-((4-(4-甲基哌嗪-1-基)苯基)氨基)嘧啶-4-基)氨基甲酸-2,6-二甲基苯酯
• LCK/SRC抑制劑(WH-4-023)
• 2,6-二甲基苯基 N-[2,4-二(甲氧基)苯基][2-[[4-(4-甲基-1-哌嗪基)苯基]氨基]-4-嘧啶基]氨基甲酸酯
• 837422-57-8
• WH-4-023, 10 mM in DMSO
• WH-4-023 USP/EP/BP
• 2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)carbamate
• )amino)pyrimidin-4-yL
• )(2-((4-(4-methyL
• DUAL LCK/SRC INHIBITOR;KIN001-112; KIN112
• 2,6-Dimethylphenyl-N-(2,4-dimethoxyphenyl)-N-[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]carbamate
• WH-4-024
• CS-1827
• DUAL LCK/SRC INHIBITOR
• WH-4-023
• 2,6-Dimethylphenyl N-[2,4-bis(methyloxy)phenyl][2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]carbamate
• 2,6-Dimethylphenyl (2,4-dimethoxyphenyl)(2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-
• WH-4-023, 837422-57-8
• WH-4-023, >=98%
• WH-4-023 2,6-DIMETHYLPHENYL 2,4-DIMETHOXYPHENYL(2-(4-(4-METHYLPIPERAZIN-1-YL)PHENYLAMINO)PYRIMIDIN-4-YL)CARBAMATE
• 2,6-dimethylphenyl (2,4-dimethoxyphenyl)(2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)carbamate WH-4-023
• KIN112
• KIN001-112
• Carbamic acid, N-(2,4-dimethoxyphenyl)-N-[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]-, 2,6-dimethylphenyl ester
• 2,6-DIMETHYLPHENYL 2,4-DIMETHOXYPHENYL(2-(4-(4-METHYLPIPERAZIN-1-YL)PHENYLAMINO)PYRIMIDIN-4-YL)CARBAMATE