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87810-56-8

中文名稱 福司曲星
英文名稱 Fostriecin
CAS 87810-56-8
分子式 C19H27O9P
分子量 430.39
MOL 文件 87810-56-8.mol
87810-56-8 結(jié)構(gòu)式 87810-56-8 結(jié)構(gòu)式

基本信息

中文別名
磷三烯菌素
英文別名
CL-1565A
Antibiotic CI-920
Antibiotic CL-1565A
Phosphotrienin, CI 920, CL 1565A, PD 110161, NSC 339638
(6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-phosphonooxy-1,7,9,11-tridecatetrenyl]-2H-pyran-2-one

應(yīng)用領(lǐng)域

用途一
Fostriecin is the most fully characterised member of a family of phosphate esters of a triene antibiotic. The antitumour potential of fostriecin has attracted considerable interest, focused on its mode of action as a topoisomerase II inhibitor. Subsequent research has focused on this metabolite's selective inhibition of protein phosphatase PP2A.
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