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69199-40-2

中文名稱 -triphosphate, Triethylammonium Salt) (1mM)
英文名稱 -triphosphate, Triethylammonium Salt) (1mM)
CAS 69199-40-2
分子式 C9H15N2O14P3
分子量 468.14
MOL 文件 69199-40-2.mol
69199-40-2 結(jié)構(gòu)式 69199-40-2 結(jié)構(gòu)式

基本信息

英文別名
-deoxy-uridine-5&rsquo
3'-Deoxyuridine-5'-triphosphate
-triphosphate, Triethylammonium Salt) (1mM)
4-dUTP (Biotin) (N-Biotin-5-(3-aminoallyl)-2&rsquo
11-dUTP (Biotin) (g-[N-(Biotin-6-amino-hexanoyl)]-5-aminoallyl-2&rsquo
16-dUTP (Biotin) g-[N-(Biotin-6-amino-hexanoyl-6-aminobutanoyl)]-5-(3-aminoallyl)-2&rsquo

物理化學性質(zhì)

密度2.010±0.06 g/cm3(Predicted)
酸度系數(shù)(pKa)0.80±0.50(Predicted)
-triphosphate, Triethylammonium Salt) (1mM)價格(試劑級)
報價日期產(chǎn)品編號產(chǎn)品名稱CAS號包裝價格
2023/03/20HY-135780-triphosphate, Triethylammonium Salt) (1mM)
3'-Deoxyuridine-5'-triphosphate
69199-40-21mg22000元

常見問題列表

生物活性
3'-Deoxyuridine-5'-triphosphate (3'-dUTP) 是一種核苷酸類似物,可抑制 DNA 依賴性 RNA 聚合酶 I 和 II (RNA polymerases I 和 II),強烈并競爭性地抑制 UTP 摻入到 RNA 中,Ki 值為 2.0 μM。
體外研究

3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is synthesized starting from cordycepin in good yield. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA by the RNA polymerases. 3'-Deoxyuridine-5'-triphosphate will be useful in studies at the molecular level on the relationship of template and substrate in RNA synthesis with chromatin, isolated nuclei or permeable cells, because it does not have any effect on poly (rA) synthesis.

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