58872-39-2
中文名稱
H-VAL-PRO-PRO-OH
英文名稱
H-VAL-PRO-PRO-OH
CAS
58872-39-2
分子式
C15H25N3O4
分子量
311.38
MOL 文件
58872-39-2.mol
更新日期
2025/01/21 16:31:09
58872-39-2 結(jié)構(gòu)式
基本信息
中文別名
(2S)-1-[(2S)-1-[(2S)-2-AMINO-3-METHYLBUTANOYL]PYRROLIDINE-2-CARBONYL]PYRROLIDINE-2-CARBOXYLIC ACID 英文別名
VPP TripeptideH-VAL-PRO-PRO-OH
L-Proline, L-valyl-L-prolyl-
(S)-1-((S)-1-((S)-2-AMino-3-Methylbutanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxylic acid
物理化學(xué)性質(zhì)
沸點(diǎn)566.4±50.0 °C(Predicted)
密度1.274±0.06 g/cm3(Predicted)
儲(chǔ)存條件Sealed in dry,2-8°C
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)3.42±0.20(Predicted)
形態(tài)Solid
顏色White to off-white
H-VAL-PRO-PRO-OH價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2025/02/08 | HY-114161 | H-Val-Pro-Pro-OH | 58872-39-2 | 5 mg | 350元 |
| 2025/02/08 | HY-114161 | H-Val-Pro-Pro-OH | 58872-39-2 | 10 mg | 550元 |
| 2025/02/08 | HY-114161 | H-Val-Pro-Pro-OH | 58872-39-2 | 25 mg | 1100元 |
常見問題列表
生物活性
H-Val-Pro-Pro-OH，是牛奶來源的脯氨酸肽衍生物，是血管緊張素 I 轉(zhuǎn)化酶 (ACE) 的抑制劑，其IC50 為 9 μM。靶點(diǎn)
IC50: 9 μM (ACE).
體外研究
H-Val-Pro-Pro-OH, a proline peptides derivative, could inhibit Angiotensin I converting enzyme (ACE), with an IC 50 of 9 μM. H-Val-Pro-Pro-OH could enhance insulin sensitivity and prevent insulin resistance in 3T3-F442A pre-adipocytes. H-Val-Pro-Pro-OH also has anti-hypertensive and anti-inflammatory functions. H-Val-Pro-Pro-OH further enhances the expression of glucose transporter 4 (GLUT4) in adipocytes and restores glucose uptake in TNF-treated adipocytes.